Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 5/20 | 0.36 |
| ▸ | KDM4A | O75164 | 2/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CHKA | P35790 | 4/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3936668 | 0.97 | ACHE (0.37) | MAPTKMT2AMEN1APAF1HSP90AA1 | |
| SCHEMBL3946285 | 0.91 | MEN1 (0.39) | MAPTKMT2AMEN1APAF1HSP90AA1 | |
| SCHEMBL3935432 | 0.90 | MEN1 (0.40) | MAPTKMT2AMEN1APAF1HSP90AA1 | |
| SCHEMBL3933444 | 0.89 | SMN1; SMN2 (0.34) | MAPTSMN1; SMN2ACHEKDM4ELMNA | |
| SCHEMBL3944256 | 0.89 | PABPC1 (0.36) | MAPTKMT2AMEN1APAF1HSP90AA1 | |
| SCHEMBL3944258 | 0.89 | PABPC1 (0.36) | MAPTKMT2AMEN1APAF1HSP90AA1 | |
| SCHEMBL3944019 | 0.88 | MAPT (0.39) | MAPTKMT2AMEN1APAF1HSP90AA1 | |
| SCHEMBL3932531 | 0.87 | ACHE (0.38) | MAPTKMT2AMEN1APAF1HSP90AA1 | |
| SCHEMBL3942922 | 0.87 | MAPT (0.36) | MAPTKMT2AMEN1APAF1HSP90AA1 | |
| SCHEMBL3935807 | 0.86 | MEN1 (0.41) | MAPTKMT2AMEN1APAF1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847250-B1 | Agents for colouring keratin fibres comprising zwitterionic azomethine dyes | PROCTER & GAMBLE (US) | 2009-12-23 | — | — | EP | claimed |
| US-7513918-B2 | Agents for coloring keratin fibers comprising zwitterionic azomethine dyes | THE PROCTER & GAMBLE COMPANY (US) | 2009-04-07 | — | — | US | claimed |
| EP-1852104-A1 | Agents for colouring keratin fibres comprising zwitterionic azomethine dyes | Wella Aktiengesellschaft (DE) | 2007-11-07 | — | — | EP | claimed |
| US-20070245501-A1 | Agents for coloring keratin fibers comprising zwitterionic azomethine dyes | WELLA OPERATIONS US, LLC | 2007-10-25 | — | — | US | claimed |
| EP-1847250-A1 | Agents for colouring keratin fibres comprising zwitterionic azomethine dyes | Wella Aktiengesellschaft (DE) | 2007-10-24 | — | — | EP | claimed |
| EP-1847250-B1 | Agents for colouring keratin fibres comprising zwitterionic azomethine dyes | PROCTER & GAMBLE (US) | 2009-12-23 | — | — | EP | disclosed |
| US-7513918-B2 | Agents for coloring keratin fibers comprising zwitterionic azomethine dyes | THE PROCTER & GAMBLE COMPANY (US) | 2009-04-07 | — | — | US | disclosed |
| EP-1852104-A1 | Agents for colouring keratin fibres comprising zwitterionic azomethine dyes | Wella Aktiengesellschaft (DE) | 2007-11-07 | — | — | EP | disclosed |
| WO-2007119228-A2 | AGENTS FOR COLOURING KERATIN FIBRES COMPRISING ZWITTERIONIC AZOMETHINE DYES | THE PROCTER & GAMBLE COMPANY (US) | 2007-10-25 | — | — | WO | disclosed |
| US-20070245501-A1 | Agents for coloring keratin fibers comprising zwitterionic azomethine dyes | WELLA OPERATIONS US, LLC | 2007-10-25 | — | — | US | disclosed |
| EP-1847250-A1 | Agents for colouring keratin fibres comprising zwitterionic azomethine dyes | Wella Aktiengesellschaft (DE) | 2007-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070245501-A1 | Agents for coloring keratin fibers comprising zwitterionic azomethine dyes | KRT18, IK, RARG | MAPT 3818/4885KMT2A 385/4885MEN1 3437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.