Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTRN | P46939 | 10/20 | 0.71 |
| ▸ | CASP3 | P42574 | 4/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2245505 | 0.83 | UTRN (1.00) | UTRNHTR2B | |
| SCHEMBL15899770 | 0.76 | UTRN (0.62) | UTRNCASP3SENP7SENP6SENP8 | |
| SCHEMBL2242304 | 0.75 | CASP3 (0.69) | UTRNCASP3SENP7SENP6SENP8 | |
| SCHEMBL11310904 | 0.75 | NPC1 (0.74) | UTRNCASP3SENP7SENP6SENP8 | |
| SCHEMBL2243999 | 0.73 | UTRN (0.70) | UTRNCASP3SENP7SENP6SENP8 | |
| SCHEMBL2089505 | 0.73 | SMN1; SMN2 (0.63) | UTRNCASP3SENP7SENP6SENP8 | |
| SCHEMBL10218249 | 0.73 | SMN1; SMN2 (0.82) | UTRNCASP3SENP7SENP6SENP8 | |
| SCHEMBL2246261 | 0.73 | MAPT (0.67) | CASP3SENP7SENP6SENP8SMN1; SMN2 | |
| SCHEMBL2242854 | 0.72 | MAPT (0.67) | CASP3SENP7SENP6SENP8MAOA | |
| SCHEMBL5052834 | 0.72 | CASP3 (0.59) | CASP3SENP7SENP6SENP8SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009021750-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2009-02-19 | — | — | WO | disclosed |