Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL560229 | 0.78 | GAA (0.55) | HPGDGAATP53RAB9ASMN1; SMN2 | |
| SCHEMBL12852993 | 0.78 | TDP1 (0.57) | HPGDTDP1GAAHTTRAB9A | |
| SCHEMBL11584854 | 0.77 | GRM4 (0.46) | HPGDGAAMEN1KMT2AHTT | |
| SCHEMBL11342920 | 0.77 | ALDH1A1 (0.52) | TDP1CYP1A2GAACYP2C19SMN1; SMN2 | |
| SCHEMBL8004244 | 0.76 | SMN1; SMN2 (0.36) | HPGDTDP1GAAHTTSMN1; SMN2 | |
| Sulfamate SCHEMBL9451318 | 0.75 | MEN1 (0.51) | HPGDTDP1CYP1A2GAACYP2C19 | |
| SCHEMBL9861682 | 0.75 | MEN1 (0.51) | HPGDTDP1CYP1A2GAACYP2C19 | |
| SCHEMBL9861109 | 0.75 | TDP1 (0.44) | HPGDTDP1CYP1A2GAACYP2C19 | |
| SCHEMBL12852989 | 0.74 | LMNA (0.49) | TDP1GAAMEN1KMT2APKM | |
| SCHEMBL19342153 | 0.74 | ALDH1A1 (0.63) | HPGDTDP1CYP1A2GAACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016216-A1 | TRIAZOLE DERIVATIVES AS SCD INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-05 | — | — | WO | disclosed |
| WO-2009016216-A1 | TRIAZOLE DERIVATIVES AS SCD INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-05 | — | — | WO | disclosed |