Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4135685 | 0.97 | HTT (0.54) | HTTSMN1; SMN2ALDH1A1LMNATSHR | |
| SCHEMBL3945166 | 0.93 | HTT (0.57) | HTTSMN1; SMN2ALDH1A1LMNATSHR | |
| SCHEMBL3951093 | 0.92 | HTT (0.55) | HTTSMN1; SMN2ALDH1A1LMNATSHR | |
| SCHEMBL3941781 | 0.92 | TP53 (0.47) | PKML3MBTL1 | |
| SCHEMBL3942911 | 0.91 | HTT (0.63) | HTTSMN1; SMN2ALDH1A1LMNATSHR | |
| SCHEMBL4157885 | 0.90 | LMNA (0.46) | HTTSMN1; SMN2ALDH1A1LMNATSHR | |
| SCHEMBL3951120 | 0.90 | TSHR (0.47) | HTTTSHR | |
| SCHEMBL3945382 | 0.90 | TP53 (0.46) | PKML3MBTL1 | |
| SCHEMBL3944960 | 0.90 | HTT (0.54) | HTTSMN1; SMN2ALDH1A1LMNATSHR | |
| SCHEMBL13941768 | 0.90 | HTT (0.53) | HTTSMN1; SMN2ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |