Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 11/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 10/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3576683 | 0.85 | MAOB (0.47) | FFAR1FFAR4CES2CES1MAOB | |
| SCHEMBL15448623 | 0.84 | MAPK8 (0.44) | CES2CES1MAOBHTR2AHTR2C | |
| SCHEMBL3940845 | 0.77 | FFAR1 (0.51) | FFAR1FFAR4MAOB | |
| SCHEMBL30637597 | 0.76 | FFAR1 (0.59) | FFAR1FFAR4TSPODRD3MAOB | |
| SCHEMBL2397247 | 0.76 | FFAR1 (0.59) | FFAR1FFAR4TSPODRD3MAOB | |
| SCHEMBL3946037 | 0.75 | TAAR1 (0.46) | FFAR1CES2CES1DAO | |
| SCHEMBL4715871 | 0.75 | MAOB (0.45) | FFAR1FFAR4CES2CES1MAOB | |
| SCHEMBL30488619 | 0.75 | MAOB (0.53) | FFAR1FFAR4CES2CES1MAOB | |
| SCHEMBL21222818 | 0.75 | MAOB (0.53) | FFAR1FFAR4CES2CES1MAOB | |
| SCHEMBL9160970 | 0.75 | MPO (0.56) | FFAR1FFAR4CES2CES1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016410-A2 | CHEMICAL COMPOUNDS 831 | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | WO | disclosed |