Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2877969 | 1.00 | CDK9 (0.31) | CDK9SCN9ACYP3A4SCN10A | |
| SCHEMBL211003 | 0.97 | CDK9 (0.32) | CDK9SCN9ACYP3A4SCN10A | |
| SCHEMBL213724 | 0.93 | ABL1 (0.32) | — | |
| SCHEMBL212277 | 0.91 | CDK9 (0.32) | CDK9SCN9ACYP3A4SCN10A | |
| SCHEMBL210996 | 0.87 | GSK3B (0.33) | CDK9SCN9ACYP3A4SCN10A | |
| SCHEMBL211004 | 0.87 | SCN9A (0.33) | CDK9SCN9ACYP3A4SCN10A | |
| SCHEMBL212989 | 0.87 | ABL1 (0.31) | — | |
| SCHEMBL211097 | 0.86 | MET (0.36) | CDK9 | |
| SCHEMBL15808666 | 0.86 | — | — | |
| SCHEMBL211802 | 0.86 | SYK (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009023193-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2009-02-19 | — | — | WO | disclosed |