Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3946077 | 0.98 | APLNR (0.33) | APLNR | |
| SCHEMBL22169703 | 0.78 | GRIN2D (0.32) | — | |
| SCHEMBL3937906 | 0.77 | APLNR (0.31) | APLNRHDAC6 | |
| SCHEMBL1693712 | 0.77 | APLNR (0.42) | APLNRHDAC6 | |
| Hydrochloric Acid SCHEMBL28446832 | 0.76 | LMNA (0.32) | — | |
| Hydrochloric Acid SCHEMBL30396919 | 0.76 | LMNA (0.32) | — | |
| Hydrochloric Acid SCHEMBL3938088 | 0.75 | APLNR (0.41) | APLNRHDAC6 | |
| SCHEMBL2161139 | 0.75 | SYK (0.31) | — | |
| SCHEMBL2161155 | 0.75 | SYK (0.31) | — | |
| SCHEMBL1395919 | 0.75 | SYK (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095712-A2 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2009-08-06 | — | — | WO | disclosed |
| WO-2009016410-A2 | CHEMICAL COMPOUNDS 831 | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | WO | disclosed |
| WO-2008132502-A1 | PYRAZOLYL-AMINO-SUBSTITUTED PYRIMIDINES AND THEIR USE FOR THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2008-11-06 | — | — | WO | disclosed |