Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4971812 | 0.98 | AOC3 (0.34) | AOC3 | |
| SCHEMBL19551100 | 0.82 | AOC3 (0.33) | AOC3 | |
| SCHEMBL3937910 | 0.81 | AOC3 (0.32) | AOC3 | |
| SCHEMBL4025184 | 0.78 | APLNR (0.43) | AOC3 | |
| Hydrochloric Acid SCHEMBL4974167 | 0.77 | APLNR (0.42) | AOC3 | |
| SCHEMBL1395922 | 0.75 | TAAR1 (0.33) | AOC3 | |
| Hydrochloric Acid SCHEMBL4974376 | 0.74 | TAAR1 (0.32) | AOC3 | |
| SCHEMBL18428175 | 0.69 | APLNR (0.34) | — | |
| SCHEMBL3946038 | 0.69 | APLNR (0.33) | — | |
| SCHEMBL12454628 | 0.68 | AOC3 (0.62) | AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095712-A2 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2009-08-06 | — | — | WO | disclosed |
| WO-2009016410-A2 | CHEMICAL COMPOUNDS 831 | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | WO | disclosed |
| WO-2008132502-A1 | PYRAZOLYL-AMINO-SUBSTITUTED PYRIMIDINES AND THEIR USE FOR THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2008-11-06 | — | — | WO | disclosed |