Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.44 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002655 | 0.78 | GRM5 (0.47) | GRM5CYP2A6ASIC3LOXL2MGLL | |
| SCHEMBL12884269 | 0.78 | GRM5 (0.60) | GRM5CYP2A6ASIC3LOXL2MGLL | |
| SCHEMBL3771142 | 0.78 | GRM5 (0.47) | GRM5CYP2A6ASIC3LOXL2MGLL | |
| SCHEMBL6006529 | 0.78 | GRM5 (0.47) | GRM5CYP2A6ASIC3LOXL2MGLL | |
| SCHEMBL56334 | 0.78 | CYP2A6 (0.48) | GRM5CYP2A6ASIC3LOXL2MGLL | |
| SCHEMBL29529198 | 0.78 | GRM5 (0.47) | GRM5CYP2A6ASIC3LOXL2MGLL | |
| SCHEMBL120641 | 0.78 | GRM5 (0.47) | GRM5CYP2A6ASIC3LOXL2MGLL | |
| SCHEMBL12884270 | 0.77 | GRM5 (0.58) | GRM5CYP2A6ASIC3LOXL2MGLL | |
| SCHEMBL12884267 | 0.75 | GRM5 (0.57) | GRM5CYP2A6ASIC3LOXL2MGLL | |
| SCHEMBL9208830 | 0.71 | GRM5 (0.53) | GRM5CYP2A6ASIC3LOXL2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2759543-B1 | CHROMENE COMPOUND AND CURABLE COMPOSITION | TOKUYAMA CORP (JP) | 2017-07-19 | — | — | EP | disclosed |
| US-9487693-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2016-11-08 | — | — | US | disclosed |
| EP-2725017-B1 | CHROMENE COMPOUND | TOKUYAMA CORP (JP) | 2016-06-29 | — | — | EP | disclosed |
| US-8916071-B2 | Chromene compound and curable composition | TOKUYAMA CORPORATION (JP) | 2014-12-23 | — | — | US | disclosed |
| EP-2554624-B1 | PHOTOCHROMIC CURABLE COMPOSITION | TOKUYAMA CORP (JP) | 2014-11-05 | — | — | EP | disclosed |
| US-20140225050-A1 | CHROMENE COMPOUND AND CURABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 2014-08-14 | — | — | US | disclosed |
| EP-2759543-A1 | CHROMENE COMPOUND AND CURABLE COMPOSITION | Tokuyama Corporation (JP) | 2014-07-30 | — | — | EP | disclosed |
| US-20140154527-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2014-06-05 | — | — | US | disclosed |
| EP-2725017-A1 | CHROMENE COMPOUND | Tokuyama Corporation (JP) | 2014-04-30 | — | — | EP | disclosed |
| CN-103635470-A | Chromene compound and curable composition | TOKUYAMA CORPROATION | 2014-03-12 | — | — | CN | disclosed |
| EP-2554624-A1 | PHOTOCHROMIC CURABLE COMPOSITION | Tokuyama Corporation (JP) | 2013-02-06 | — | — | EP | disclosed |
| US-20130015416-A1 | PHOTOCHROMIC CURABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 2013-01-17 | — | — | US | disclosed |
| EP-2479171-A1 | CHROMENE COMPOUND | Tokuyama Corporation (JP) | 2012-07-25 | — | — | EP | disclosed |
| US-20120170098-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2012-07-05 | — | — | US | disclosed |
| CN-102471304-A | Chromene compound | TOKUYAMA CORP | 2012-05-23 | — | — | CN | disclosed |
| US-7521004-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2009-04-21 | — | — | US | disclosed |
| EP-1674460-B1 | CHROMENE COMPOUND | TOKUYAMA CORP (JP) | 2009-01-21 | — | — | EP | disclosed |
| US-20070215844-A1 | Chromene Compound | TOKUYAMA CORPORATION (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1674460-A1 | CHROMENE COMPOUND | Tokuyama Corporation (JP) | 2006-06-28 | — | — | EP | disclosed |
| US-6384065-B1 | CONTROL THE FUNCTIONS OF PROTEINS SUCH AS ENZYMES AND RECEPTOR FORTREATING INFLAMMATORY DISEASES SUCH AS RHEUMATOID ARTHRITIS, | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120170098-A1 | CHROMENE COMPOUND | CRY2, CRY1, SUN2 | GRM5 4420/4885CYP2A6 763/4885ASIC3 2014/4885 |
| US-20070215844-A1 | Chromene Compound | CRY2, TYR, CRY1 | GRM5 3486/4885CYP2A6 532/4885ASIC3 1830/4885 |
| US-20140225050-A1 | CHROMENE COMPOUND AND CURABLE COMPOSITION | CRY2, CRY1, CDYL | GRM5 4208/4885CYP2A6 798/4885ASIC3 1309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.