Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | DRD3 | P35462 | 4/20 | 0.36 |
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 5/20 | 0.35 |
| ▸ | IRS1 | P35568 | 3/20 | 0.35 |
| ▸ | GAB1 | Q13480 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3945247 | 0.95 | FAAH (0.36) | FAAHDRD2DRD3HTR6HTR2A | |
| SCHEMBL3944410 | 0.95 | FAAH (0.39) | FAAHDRD2DRD3HTR6HTR2A | |
| SCHEMBL3942639 | 0.93 | FAAH (0.40) | FAAHDRD2DRD3HTR6HTR2A | |
| SCHEMBL981069 | 0.86 | FAAH (0.39) | FAAHDRD2DRD3HTR6HTR2A | |
| SCHEMBL980126 | 0.79 | AKT1 (0.46) | DRD2DRD3HTR6HTR2AHTR2C | |
| SCHEMBL3941311 | 0.78 | S1PR1 (0.42) | FAAHCA2CA12CA1CA9 | |
| SCHEMBL979818 | 0.78 | FAAH (0.37) | FAAHAKT1IRS1GAB1LMNA | |
| SCHEMBL977573 | 0.78 | DRD2 (0.40) | FAAHDRD2DRD3HTR6HTR2A | |
| SCHEMBL977637 | 0.78 | FAAH (0.38) | FAAHDRD2DRD3HTR6HTR2A | |
| SCHEMBL1081760 | 0.78 | FAAH (0.38) | FAAHAKT1IRS1GAB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009015485-A1 | CYCLIC INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK (CA) | 2009-02-05 | — | — | WO | disclosed |