SCHEMBL3946484

SCHEMBL3946484

FC(F)(F)c1cc(C2=Cc3ccccc3C2[Hf](Cl)(Cl)C2C(c3cc(C(F)(F)F)cc(C(F)(F)F)c3)=Cc3ccccc32)cc(C(F)(F)F)c1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
P2RX1 P51575 1/20 0.31
RORB Q92753 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6927035 0.96 CNR1 (0.34) CNR1CNR2P2RX1
SCHEMBL8585034 0.92 NOTUM (0.32)
SCHEMBL6285169 0.86 RXRA (0.31)
SCHEMBL7928686 0.80 CNR1 (0.33) CNR1CNR2P2RX1
SCHEMBL6285712 0.78 CFTR (0.33)
SCHEMBL7526333 0.78
SCHEMBL6930164 0.78 TACR1 (0.32)
SCHEMBL6930680 0.78 CNR1 (0.35) CNR1CNR2P2RX1
Hydrochloric Acid SCHEMBL7937854 0.78 CNR1 (0.35) CNR1CNR2P2RX1
SCHEMBL7937856 0.77 CNR1 (0.33) CNR1CNR2P2RX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0802935-A4 THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS UNIV LELAND STANFORD JUNIOR (US) 1998-09-30 EP claimed
EP-0802935-A1 THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1997-10-29 EP claimed
US-5594080-A POLYMERIZATION CATALYSIS OF METALLOCENES WITH CYCLOPENTADIENE AND METALS LELAND STANFORD, JR. UNIVERSITY (US) 1997-01-14 US claimed
WO-1995025757-A1 THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1995-09-28 WO claimed
US-7592408-B2 Olefin copolymers containing hydrolytically cleavable linkages and use thereof in degradable products SRI INTERNATIONAL (US) 2009-09-22 US disclosed
US-20080227940-A1 Olefin Copolymers Containing Hydrolytically Cleavable Linkages and Use Thereof In Degradable Products SRI INTERNATIONAL (US) 2008-09-18 US disclosed
US-7399817-B2 Olefin copolymers containing hydrolytically cleavable linkages and use thereof in degradable products SRI INTERNATIONAL (US) 2008-07-15 US disclosed
US-7037992-B2 Olefin copolymers containing hydrolytically cleavable linkages and use thereof in degradable products SRI INTERNATIONAL (US) 2006-05-02 US disclosed
US-20060079654-A1 Olefin copolymers containing hydrolytically cleavable linkages and use thereof in degradable products SRI INTERNATIONAL (US) 2006-04-13 US disclosed
EP-1603958-A1 OLEFIN COPOLYMERS CONTAINING HYDROLYTICALLY CLEAVABLE LINKAGES AND USE THEREOF IN DEGRADABLE PRODUCTS Sri International (US) 2005-12-14 EP disclosed
US-6960550-B2 Catalyst systems for high melting thermoplastic elastomeric α-olefin polymers and plastomers THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2005-11-01 US disclosed
WO-2004083266-A1 OLEFIN COPOLYMERS CONTAINING HYDROLYTICALLY CLEAVABLE LINKAGES AND USE THEREOF IN DEGRADABLE PRODUCTS SRI INTERNATIONAL (US) 2004-09-30 WO disclosed
WO-2001023448-A1 HYDROLYTICALLY DEGRADABLE OLEFIN COPOLYMERS SRI INTERNATIONAL (US) 2001-04-05 WO disclosed
US-6169151-B1 MADE BY POLYMERIZING ETHYLENE AND ALPHA-OLEFIN(S) USING AN UNBRIDGED, ROTATING, NON-RIGID FLUXIONAL METALLOCENE CATALYST AND COCATALYST; CRYSTALLIZABLE ELASTOMERIC COPOLYMER PRODUCT HAS HIGHER MELTING POINT, NARROW COMPOSITION DISTRIBUTION THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2001-01-02 US disclosed
US-6160064-A POLYMERIZING MONOMERS IN PRESENCE OF CATALYST SYSTEM COMPRISING UNBRIDGED FLUXIONAL METALLOCENE AND COCATALYST, INTRODUCING ETHYLENE INTO SYSTEM TO INDUCE POLYMERIZATION RATE ENHANCEMENT/ELASTOMERIC PROPERTY ENHANCING EFFECTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2000-12-12 US disclosed
US-5969070-A HOMOGENEOUS COMPOSITION FORMED FROM LINEAR OR BRANCHED CHAIN C3 TO C10 MONOMERS SUCH AS PROPYLENE, 1-BUTENE, 1-PENTENE, 4-METHYL-1-PENTENE, 1-HEXENE AND MIXTURES THEREOF, COMPRISING ALTERNATING ISOTACTIC AND ATACTIC DISASTEREOSEQUENCES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1999-10-19 US disclosed
WO-1999035171-A1 HIGH-MELTING POLYOLEFIN COPOLYMER ELASTOMERS, CATALYSTS AND METHODS OF SYNTHESIS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JR. UNIVERSITY (US) 1999-07-15 WO disclosed
EP-0802935-A4 THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS UNIV LELAND STANFORD JUNIOR (US) 1998-09-30 EP disclosed
EP-0802935-A1 THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1997-10-29 EP disclosed
WO-1995025757-A1 THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1995-09-28 WO disclosed