SCHEMBL7928686

SCHEMBL7928686

FC(F)(F)c1cc(C2=Cc3ccccc3C2[Hf](Cl)Cl)cc(C(F)(F)F)c1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
P2RX1 P51575 1/20 0.31
PTAFR P25105 1/20 0.30
IKBKB O14920 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7937655 0.86 RXRA (0.31) PTAFR
SCHEMBL3946484 0.80 CNR1 (0.33) CNR1CNR2P2RX1
SCHEMBL4089941 0.78 CFTR (0.33)
SCHEMBL6290272 0.78 TACR1 (0.32)
Hydrochloric Acid SCHEMBL7937854 0.78 CNR1 (0.35) CNR1CNR2P2RX1
SCHEMBL6930680 0.78 CNR1 (0.35) CNR1CNR2P2RX1IKBKB
SCHEMBL7937856 0.77 CNR1 (0.33) CNR1CNR2P2RX1
SCHEMBL6290545 0.77 CNR1 (0.33) CNR1CNR2P2RX1
SCHEMBL6927035 0.77 CNR1 (0.34) CNR1CNR2P2RX1
Hydrochloric Acid SCHEMBL3943546 0.77 CNR1 (0.35) CNR1CNR2P2RX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1157047-A1 LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS BP Corporation North America Inc. (US) 2001-11-28 EP disclosed
WO-2000035975-A1 LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS BP CORPORATION NORTH AMERICA INC. (US) 2000-06-22 WO disclosed