Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 2/20 | 0.42 |
| ▸ | RARG | P13631 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3946489 | 1.00 | SRD5A2 (0.46) | SRD5A2HDAC1RARBRARGMEN1 | |
| SCHEMBL3946491 | 1.00 | SRD5A2 (0.46) | SRD5A2HDAC1RARBRARGMEN1 | |
| SCHEMBL3940623 | 0.84 | NR4A1 (0.49) | SRD5A2HDAC1CYP1A2EPHX2RAB9A | |
| SCHEMBL3940626 | 0.84 | NR4A1 (0.49) | SRD5A2HDAC1CYP1A2EPHX2RAB9A | |
| SCHEMBL3939814 | 0.84 | NR4A1 (0.49) | SRD5A2HDAC1CYP1A2EPHX2RAB9A | |
| SCHEMBL4092546 | 0.83 | SRD5A2 (0.49) | SRD5A2HDAC1RARBRARGMEN1 | |
| SCHEMBL3937848 | 0.83 | SRD5A2 (0.49) | SRD5A2HDAC1RARBRARGMEN1 | |
| SCHEMBL3943637 | 0.81 | ALDH1A1 (0.55) | SRD5A2MEN1KMT2AALDH1A1HTT | |
| SCHEMBL3943639 | 0.81 | ALDH1A1 (0.55) | SRD5A2MEN1KMT2AALDH1A1HTT | |
| SCHEMBL3943635 | 0.81 | ALDH1A1 (0.55) | SRD5A2MEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2009-08-13 | — | — | US | disclosed |
| EP-2050734-A1 | PENTADIENAMIDE DERIVATIVE | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | PRMT1, REN, NGLY1 | SRD5A2 798/4885HDAC1 37/4885RARB 2135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.