Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 6/20 | 0.43 |
| ▸ | CASR | P41180 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3951253 | 0.89 | NPY5R (0.46) | NPY5RCASRGAA | |
| SCHEMBL3951648 | 0.80 | TSPO (0.37) | CASRTSPO | |
| SCHEMBL1384551 | 0.79 | CASR (0.46) | CASR | |
| SCHEMBL3945147 | 0.78 | TSPO (0.37) | CASRGAATSPO | |
| SCHEMBL3443137 | 0.75 | CASR (0.44) | CASRTSPO | |
| SCHEMBL3946983 | 0.73 | CASR (0.43) | CASRTSPO | |
| SCHEMBL3943937 | 0.73 | NPY5R (0.47) | NPY5RCASRGAA | |
| SCHEMBL3951753 | 0.73 | CASR (0.37) | CASR | |
| SCHEMBL4036518 | 0.72 | CASR (0.40) | CASR | |
| SCHEMBL3442709 | 0.72 | ATM (0.50) | CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718632-B1 | PYRIMIDINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | SANOFI AVENTIS (FR) | 2009-04-22 | — | — | EP | claimed |