Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3949402 | 0.94 | PKM (0.48) | RXFP1PKMMEN1KMT2A | |
| SCHEMBL3942889 | 0.91 | RXFP1 (0.46) | RXFP1TSHRHTTMAPK10MEN1 | |
| SCHEMBL3946330 | 0.90 | MEN1 (0.54) | RXFP1TSHRHTTMAPK10MEN1 | |
| SCHEMBL3944881 | 0.89 | RXFP1 (0.65) | RXFP1PKMTSHRHTTMEN1 | |
| SCHEMBL3945209 | 0.89 | HTT (0.56) | RXFP1PKMTSHRHTTMEN1 | |
| SCHEMBL3939707 | 0.89 | RXFP1 (0.44) | RXFP1TSHRHTTMAPK10MEN1 | |
| SCHEMBL3947170 | 0.89 | PKM (0.61) | RXFP1PKMTSHRHTTMAPK10 | |
| SCHEMBL3941629 | 0.87 | PKM (0.57) | RXFP1PKMTSHRHTTMAPK10 | |
| SCHEMBL3952043 | 0.86 | RXFP1 (0.47) | RXFP1TSHRHTTMAPK10 | |
| SCHEMBL3947537 | 0.85 | MEN1 (0.50) | PKMTSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |