Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3950563 | 0.94 | MEN1 (0.42) | MEN1KMT2A | |
| SCHEMBL3943432 | 0.90 | RXFP1 (0.51) | RXFP1TSHRHTTMAPK10MEN1 | |
| SCHEMBL3950864 | 0.89 | LMNA (0.50) | TSHRHTTMEN1KMT2A | |
| SCHEMBL3945499 | 0.89 | TSHR (0.49) | RXFP1TSHRHTTMAPK10MEN1 | |
| SCHEMBL3942889 | 0.89 | RXFP1 (0.46) | RXFP1TSHRHTTMAPK10MEN1 | |
| SCHEMBL3946633 | 0.89 | RXFP1 (0.52) | RXFP1TSHRHTTMAPK10MEN1 | |
| SCHEMBL3945413 | 0.88 | MEN1 (0.52) | MEN1KMT2A | |
| SCHEMBL3946330 | 0.88 | MEN1 (0.54) | RXFP1TSHRHTTMAPK10MEN1 | |
| SCHEMBL3943104 | 0.88 | RXFP1 (0.44) | RXFP1TSHRHTTMAPK10MEN1 | |
| SCHEMBL4521555 | 0.88 | RXFP1 (0.59) | RXFP1TSHRHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |