Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13761272 | 0.90 | HSD11B1 (0.41) | TRPV1HSD11B1 | |
| SCHEMBL3884755 | 0.88 | HSD11B1 (0.45) | TRPV1HSD11B1 | |
| SCHEMBL3877102 | 0.88 | TRPV1 (0.44) | TRPV1HSD11B1 | |
| SCHEMBL3877637 | 0.87 | HSD11B1 (0.46) | HSD11B1 | |
| SCHEMBL3880138 | 0.83 | HSD11B1 (0.43) | TRPV1HSD11B1 | |
| SCHEMBL3880146 | 0.83 | HSD11B1 (0.43) | TRPV1HSD11B1 | |
| SCHEMBL3876842 | 0.83 | HSD11B1 (0.49) | TRPV1HSD11B1 | |
| SCHEMBL13761395 | 0.83 | HSD11B1 (0.43) | TRPV1HSD11B1 | |
| SCHEMBL3878661 | 0.82 | HSD11B1 (0.42) | TRPV1HSD11B1 | |
| SCHEMBL3878656 | 0.82 | HSD11B1 (0.42) | TRPV1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566712-B2 | Biaryl piperazinyl-pyridine analogues | NEUROGEN CORPORATION (US) | 2009-07-28 | — | — | US | disclosed |