Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3946586 | 0.90 | ALDH1A1 (0.54) | ALDH1A1MAPTL3MBTL1KDM4EHSD17B10 | |
| SCHEMBL3950369 | 0.90 | ALDH1A1 (0.55) | ALDH1A1MAPTL3MBTL1KDM4EHSD17B10 | |
| SCHEMBL3950431 | 0.89 | MAPT (0.60) | ALDH1A1MAPTL3MBTL1KDM4EHSD17B10 | |
| SCHEMBL4355930 | 0.88 | MAPT (0.57) | ALDH1A1MAPTL3MBTL1KDM4ELMNA | |
| SCHEMBL7937758 | 0.88 | ALDH1A1 (0.61) | ALDH1A1MAPTL3MBTL1KDM4EHSD17B10 | |
| SCHEMBL4158477 | 0.88 | MAPT (0.60) | ALDH1A1MAPTL3MBTL1KDM4EHSD17B10 | |
| SCHEMBL3950434 | 0.87 | ALDH1A1 (0.64) | ALDH1A1MAPTL3MBTL1KDM4EHSD17B10 | |
| SCHEMBL3950920 | 0.86 | ALDH1A1 (0.62) | ALDH1A1MAPTL3MBTL1KDM4EHSD17B10 | |
| SCHEMBL4211551 | 0.85 | MAPT (0.59) | ALDH1A1MAPTL3MBTL1KDM4EHSD17B10 | |
| SCHEMBL3946900 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPTL3MBTL1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |