SCHEMBL394717

SCHEMBL394717

Nc1cc(N)cc(C(F)(F)F)c1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.56
MAPK1 P28482 1/20 0.56
KIF11 P52732 2/20 0.46
NR2E1 Q9Y466 1/20 0.44
PTPN5 P54829 2/20 0.41
ALDH1A1 P00352 4/20 0.41
IDO1 P14902 2/20 0.41
MAPT P10636 1/20 0.41
NOS3 P29474 1/20 0.41
NOS2 P35228 1/20 0.41
CES2 O00748 1/20 0.40
GLA P06280 1/20 0.39
POLB P06746 1/20 0.39
GAA P10253 1/20 0.39
PKM P14618 1/20 0.35
BACE1 P56817 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27859051 0.97 TSHR (0.54) TSHRMAPK1KIF11NR2E1PTPN5
Hydrochloric Acid SCHEMBL9741395 0.97 TSHR (0.54) TSHRMAPK1KIF11NR2E1PTPN5
SCHEMBL130383 0.94 TSHR (0.56) TSHRMAPK1KIF11NR2E1PTPN5
Iodide SCHEMBL31550893 0.91 TSHR (0.54) TSHRMAPK1KIF11NR2E1PTPN5
SCHEMBL29576147 0.86 TSHR (0.50) TSHRMAPK1KIF11NR2E1PTPN5
SCHEMBL716180 0.86 TSHR (0.50) TSHRMAPK1KIF11NR2E1PTPN5
SCHEMBL8999883 0.86 TSHR (0.50) TSHRMAPK1KIF11NR2E1PTPN5
SCHEMBL8999915 0.86 TSHR (0.50) TSHRMAPK1KIF11NR2E1PTPN5
SCHEMBL29361649 0.84 TSHR (0.48) TSHRMAPK1KIF11NR2E1PTPN5
SCHEMBL30600349 0.84 KIF11 (0.44) TSHRMAPK1KIF11NR2E1PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1832 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080406-A High-temperature-resistant and thermally-dimensionally-stable soluble polyimide resin and preparation method and application thereof 2026-05-26 CN claimed
CN-122032490-A Preparation and application of neon/helium separation carbon molecular sieve adsorbent 中国科学院过程工程研究所 2026-05-15 CN claimed
EP-4616929-A1 POLYAMIDE COMPOSITE MEMBRANE AND PREPARATION METHOD THEREFOR Wanhua Chemical Group Co., Ltd. (CN) 2025-09-17 EP claimed
CN-120118361-A High-temperature-resistant colorless polyimide film and preparation method thereof 太湖聚智新材料科技有限公司 2025-06-10 CN claimed
CN-120040699-A Covalent organic framework material and preparation method and application thereof 贵州师范学院 2025-05-27 CN claimed
WO-2025100608-A1 POLYIMIDE COMPOSITION, MANUFACTURING METHOD THEREFOR, AND POLYIMIDE FILM USING SAME 엘지전자 주식회사 2025-05-15 WO claimed
WO-2025100607-A1 POLYIMIDE COMPOSITION, PREPARATION METHOD THEREFOR, AND POLYIMIDE FILM USING SAME 엘지전자 주식회사 2025-05-15 WO claimed
CN-119431741-A Reactive adjustable curing agent, high-modulus epoxy resin matrix and preparation method thereof 航天材料及工艺研究所 2025-02-14 CN claimed
CN-119431721-A Polyurethane material with ion interaction and preparation method thereof 中国科学院兰州化学物理研究所 2025-02-14 CN claimed
CN-119401058-A Polyimide microsphere coated modified battery diaphragm and lithium ion battery 浙江中科玖源新材料有限公司 2025-02-07 CN claimed
EP-0509446-A2 Preparation of 3,5-diaminobenzotrifluoride OCCIDENTAL CHEMICAL CORPORATION (US) 1992-10-21 EP claimed
US-5144076-A Preparation of 3,5-diamino benzotrifluoride OCCIDENTAL CHEMICAL CORPORATION (US) 1992-09-01 US claimed
US-5130490-A Purification of 3,5-diaminobenzotrifluoride by selective precipitation of the hydrochloride salt OCCIDENTAL CHEMICAL CORPORATION (US) 1992-07-14 US claimed
EP-0490115-A1 Process for the preparation of 3,5-diaminobenzotrifluoride OCCIDENTAL CHEMICAL CORPORATION (US) 1992-06-17 EP claimed
US-5122563-A Heat resistant; composites, adhesives; amine having at least one trifluoromethyl group AMERICAN CYANAMID COMPANY (US) 1992-06-16 US claimed
EP-0484767-A1 Preparation of 3,5-diamino benzotrifluoride OCCIDENTAL CHEMICAL CORPORATION (US) 1992-05-13 EP claimed
EP-0177122-B1 ACRYLAMIDE DERIVATIVES Nippon Paint Co., Ltd. (JP) 1992-04-01 EP claimed
US-5061781-A From dianhydrides and either diaminobenzotrifluoromethanes or bis(trifluoromethyl) oxydianilines and endcapped AMERICAN CYANAMID COMPANY (US) 1991-10-29 US claimed
US-4935413-A ELASTICITY, ADHESION AND DISPERSIBILITY NIPPON PAINT CO., LTD. (JP) 1990-06-19 US claimed
US-4876329-A LOW DIELECTRIC CONSTANT, COLORLESS, HEAT STABILITY, HIGH GLASS TRANSITION TEMPERATURE; ELECTRONICS USE AMOCO CORPORATION (US) 1989-10-24 US claimed