SCHEMBL3947348

SCHEMBL3947348

CC1(C)c2ccccc2CC1c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 5/20 0.47
MAOA P21397 5/20 0.47
MAOB P27338 5/20 0.47
SIGMAR1 Q99720 1/20 0.41
CYP3A4 P08684 2/20 0.41
MEN1 O00255 1/20 0.41
CYP2D6 P10635 1/20 0.41
ALOX15 P16050 1/20 0.41
CYP2C19 P33261 1/20 0.41
KMT2A Q03164 1/20 0.41
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
BCHE P06276 1/20 0.41
CHRM5 P08912 1/20 0.41
TSHR P16473 1/20 0.41
ALOX12 P18054 1/20 0.41
NFKB1 P19838 1/20 0.41
MAPK1 P28482 1/20 0.41
PRCP P42785 1/20 0.41
GRIN1 Q05586 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4541268 0.77 KDM1A (0.38) KDM1AMAOAMAOBPRCP
SCHEMBL3148715 0.77 KDM1A (0.47) KDM1AMAOAMAOB
SCHEMBL28180549 0.77 KDM1A (0.39) KDM1AMAOAMAOBSIGMAR1CYP3A4
Benzene SCHEMBL28485309 0.76 SIGMAR1 (0.44) SIGMAR1CYP3A4MEN1CYP2D6ALOX15
SCHEMBL7782470 0.76 KDM1A (0.43) KDM1AMAOAMAOBSIGMAR1PRCP
SCHEMBL8887073 0.75 KDM1A (0.38) KDM1AMAOAMAOBSIGMAR1
SCHEMBL11295093 0.74 KDM1A (0.46) KDM1AMAOBSIGMAR1CYP3A4MEN1
SCHEMBL414650 0.74 CYP3A4 (0.44) SIGMAR1CYP3A4MEN1CYP2D6ALOX15
SCHEMBL21845155 0.74 KDM1A (0.46) KDM1AMAOBSIGMAR1CYP3A4MEN1
SCHEMBL29662225 0.73 KDM1A (0.52) KDM1AMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2049550-A1 METHOD FOR PRODUCING COPPER-CONTAINING ORGANOMETALLIC FRAMEWORK MATERIAL BASF SE (DE) 2009-04-22 EP disclosed
WO-2008012216-A1 METHOD FOR PRODUCING COPPER-CONTAINING ORGANOMETALLIC FRAMEWORK MATERIAL BASF SE (DE) 2008-01-31 WO disclosed