Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.63 |
| ▸ | KDR | P35968 | 16/20 | 0.63 |
| ▸ | FLT4 | P35916 | 4/20 | 0.60 |
| ▸ | AURKA | O14965 | 3/20 | 0.60 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.60 |
| ▸ | TEK | Q02763 | 2/20 | 0.60 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.60 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.60 |
| ▸ | FLT1 | P17948 | 2/20 | 0.58 |
| ▸ | BRAF | P15056 | 1/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13868777 | 0.96 | EGFR (0.68) | EGFRKDRFLT4AURKAPDGFRB | |
| SCHEMBL3945749 | 0.95 | KDR (0.63) | EGFRKDRFLT4AURKAPDGFRB | |
| SCHEMBL3946268 | 0.93 | AURKA (0.64) | EGFRKDRFLT4AURKAPDGFRB | |
| SCHEMBL3953822 | 0.92 | EGFR (0.67) | EGFRKDRFLT4AURKAPDGFRB | |
| SCHEMBL3953826 | 0.92 | AURKA (0.63) | EGFRKDRFLT4AURKAPDGFRB | |
| SCHEMBL3954550 | 0.91 | EGFR (0.67) | EGFRKDRFLT4AURKAPDGFRB | |
| SCHEMBL3946948 | 0.90 | EGFR (0.68) | EGFRKDRFLT4AURKAPDGFRB | |
| SCHEMBL3947514 | 0.90 | EGFR (0.65) | EGFRKDRFLT4AURKAPDGFRB | |
| SCHEMBL1504947 | 0.89 | KDR (0.62) | EGFRKDRFLT4AURKAPDGFRB | |
| SCHEMBL3948194 | 0.88 | EGFR (0.68) | EGFRKDRFLT4AURKAPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514460-B2 | Benzazole analogues and uses thereof | 4SC AG (DE) | 2009-04-07 | — | — | US | disclosed |
| US-7514460-B2 | Benzazole analogues and uses thereof | 4SC AG (DE) | 2009-04-07 | — | — | US | disclosed |
| US-7514460-B2 | Benzazole analogues and uses thereof | 4SC AG (DE) | 2009-04-07 | — | — | US | disclosed |
| US-20060135782-A1 | Benzazole analogues and uses thereof | 4SC AG (DE) | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135782-A1 | Benzazole analogues and uses thereof | DCK, SBK3, DAPK3 | EGFR 437/4885KDR 1657/4885FLT4 1741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.