Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3938015 | 0.85 | AGBL2 (0.32) | AGBL2 | |
| SCHEMBL1396052 | 0.85 | AGBL2 (0.38) | DPP4DPP9AGBL2GRM5CCNT1 | |
| SCHEMBL3232383 | 0.76 | CCNT1 (0.33) | DPP4DPP9AGBL2CCNT1CCNE1 | |
| SCHEMBL3232389 | 0.76 | CCNT1 (0.33) | DPP4DPP9AGBL2CCNT1CCNE1 | |
| SCHEMBL3942053 | 0.72 | HPGD (0.39) | DPP4DPP9MAPK1AGBL2GRM5 | |
| SCHEMBL4019098 | 0.69 | MAPK1 (0.39) | MAPK1AGBL2GRM5 | |
| SCHEMBL12780425 | 0.69 | AGBL2 (0.41) | DPP4DPP9AGBL2GRM5 | |
| SCHEMBL12363473 | 0.68 | CCNT1 (0.33) | DPP4DPP9AGBL2GRM5CCNT1 | |
| SCHEMBL2161139 | 0.68 | SYK (0.31) | — | |
| SCHEMBL2161155 | 0.68 | SYK (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016410-A2 | CHEMICAL COMPOUNDS 831 | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | WO | disclosed |