Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947993 | 0.85 | DPP4 (0.31) | AGBL2 | |
| SCHEMBL1395919 | 0.80 | SYK (0.31) | SYK | |
| SCHEMBL2161155 | 0.80 | SYK (0.31) | SYK | |
| SCHEMBL2161139 | 0.80 | SYK (0.31) | SYK | |
| SCHEMBL30318587 | 0.79 | MAPT (0.31) | — | |
| Hydrochloric Acid SCHEMBL3939583 | 0.79 | SYK (0.30) | SYK | |
| SCHEMBL3937906 | 0.75 | APLNR (0.31) | KDM4EALDH1A1KMT2A | |
| SCHEMBL4019098 | 0.75 | MAPK1 (0.39) | AGBL2 | |
| SCHEMBL26743053 | 0.75 | CA1 (0.43) | KMT2A | |
| SCHEMBL4198174 | 0.74 | APLNR (0.33) | AGBL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016410-A2 | CHEMICAL COMPOUNDS 831 | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | WO | disclosed |
| WO-2008132502-A1 | PYRAZOLYL-AMINO-SUBSTITUTED PYRIMIDINES AND THEIR USE FOR THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2008-11-06 | — | — | WO | disclosed |