Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 11/20 | 0.56 |
| ▸ | BCR | P11274 | 9/20 | 0.56 |
| ▸ | PDGFRA | P16234 | 9/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.56 |
| ▸ | EGFR | P00533 | 4/20 | 0.56 |
| ▸ | PRKCA | P17252 | 4/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.55 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.53 |
| ▸ | KIT | P10721 | 3/20 | 0.48 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | BTK | Q06187 | 1/20 | 0.48 |
| ▸ | ITK | Q08881 | 1/20 | 0.48 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3359717 | 0.89 | ABL1 (0.55) | ABL1BCRPDGFRAPDGFRBEGFR | |
| SCHEMBL4373261 | 0.86 | CAMKK2 (0.53) | ABL1BCRPDGFRAPDGFRBEGFR | |
| SCHEMBL3359726 | 0.86 | ABL1 (0.51) | ABL1BCRPDGFRAPDGFRBEGFR | |
| SCHEMBL3359707 | 0.86 | ABL1 (0.54) | ABL1BCRPDGFRAPDGFRBEGFR | |
| SCHEMBL29707254 | 0.85 | ABL1 (0.71) | ABL1BCRPDGFRAPDGFRBEGFR | |
| SCHEMBL533540 | 0.85 | ABL1 (0.71) | ABL1BCRPDGFRAPDGFRBEGFR | |
| SCHEMBL22169828 | 0.85 | CAMKK2 (0.59) | ABL1BCRPDGFRAPDGFRBEGFR | |
| SCHEMBL22169842 | 0.84 | CAMKK2 (0.63) | ABL1BCRPDGFRAPDGFRBEGFR | |
| SCHEMBL3949460 | 0.83 | CAMKK2 (0.53) | ABL1BCRPDGFRAPDGFRBEGFR | |
| SCHEMBL22169873 | 0.82 | CAMKK2 (0.74) | ABL1BCRPDGFRAPDGFRBEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109991-A2 | NOVEL HYDRAZIDE CONTAINING TYROSINE KINASE INHIBITORS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD., (IN) | 2009-09-11 | — | — | WO | claimed |
| EP-1922309-B1 | N-PHENYL-2-PYRIMIDINE-AMINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | IL YANG PHARM CO LTD (KR) | 2014-05-21 | — | — | EP | disclosed |
| WO-2009109991-A2 | NOVEL HYDRAZIDE CONTAINING TYROSINE KINASE INHIBITORS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD., (IN) | 2009-09-11 | — | — | WO | disclosed |
| US-7501424-B2 | N-phenyl-2-pyrimidine-amine derivatives and process for the preparation thereof | IL-YANG PHARM. CO., LTD. (KR) | 2009-03-10 | — | — | US | disclosed |
| EP-1922309-A1 | N-PHENYL-2-PYRIMIDINE-AMINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Il Yang Pharm. Co. Ltd. (KR) | 2008-05-21 | — | — | EP | disclosed |
| US-20080096899-A1 | N-Phenyl-2-Pyrimidine-Amine Derivatives and Process for the Preparation Thereof | IL-YANG PHARM. CO., LTD. (KR) | 2008-04-24 | — | — | US | disclosed |
| WO-2007018325-A1 | N-PHENYL-2-PYRIMIDINE-AMINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | IL-YANG PHARM. CO., LTD. (KR) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096899-A1 | N-Phenyl-2-Pyrimidine-Amine Derivatives and Process for the Preparation Thereof | ITPA, TYMP, THPO | ABL1 451/4885BCR 990/4885PDGFRA 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.