Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTRN | P46939 | 6/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | AHR | P35869 | 1/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.65 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3944431 | 0.81 | UTRN (0.77) | UTRNCYP1A2AHRHDAC6KMT2A | |
| SCHEMBL17479807 | 0.79 | ALDH1A1 (0.60) | CYP1A2MCOLN3TSHRKMT2AMEN1 | |
| Ezutromid SCHEMBL31080435 | 0.79 | UTRN (1.00) | UTRNCYP1A2AHRHDAC6KMT2A | |
| Ezutromid SCHEMBL30791155 | 0.79 | UTRN (1.00) | UTRNCYP1A2AHRHDAC6KMT2A | |
| Ezutromid SCHEMBL732212 | 0.79 | UTRN (1.00) | UTRNCYP1A2AHRHDAC6KMT2A | |
| Ezutromid SCHEMBL29376738 | 0.79 | UTRN (1.00) | UTRNCYP1A2AHRHDAC6KMT2A | |
| SCHEMBL17479721 | 0.78 | MAPK1 (0.56) | CYP1A2AHRTSHRKMT2AMEN1 | |
| SCHEMBL3169939 | 0.77 | MCOLN3 (0.97) | MCOLN3TSHRKMT2AMEN1SMN1; SMN2 | |
| Ezutromid SCHEMBL3954452 | 0.76 | UTRN (0.84) | UTRNCYP1A2AHRHDAC6KMT2A | |
| SCHEMBL3947253 | 0.76 | UTRN (0.77) | UTRNCYP1A2AHRHDAC6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009021750-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2009-02-19 | — | — | WO | disclosed |