Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24155693 | 0.81 | NPC1 (0.57) | RAB9ANPC1SMN1; SMN2ALDH1A1PRKD1 | |
| SCHEMBL28209001 | 0.78 | NPC1 (0.49) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL24586979 | 0.77 | NPC1 (0.52) | RAB9ANPC1SMN1; SMN2ALDH1A1PRKD1 | |
| SCHEMBL29386674 | 0.75 | ALDH1A1 (0.86) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL182655 | 0.75 | ALDH1A1 (0.86) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL3739909 | 0.75 | ALDH1A1 (0.86) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL24156017 | 0.75 | EPHB4 (0.47) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL1156058 | 0.74 | NQO2 (0.50) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL24156019 | 0.74 | NPC1 (0.52) | RAB9ANPC1SMN1; SMN2ALDH1A1PRKD1 | |
| SCHEMBL9513153 | 0.73 | ALDH1A1 (0.91) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009021750-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2009-02-19 | — | — | WO | disclosed |