SCHEMBL1156058

SCHEMBL1156058

c1ccc2cc3ocnc3cc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 1/20 0.50
DYRK1A Q13627 2/20 0.44
CTNNB1 P35222 4/20 0.42
WNT3A P56704 4/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 2/20 0.40
CHRNB2 P17787 1/20 0.40
CHRNA4 P43681 1/20 0.40
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40
KMT2A Q03164 1/20 0.40
PI4KA P42356 1/20 0.37
PI4K2B Q8TCG2 1/20 0.37
PI4K2A Q9BTU6 1/20 0.37
PI4KB Q9UBF8 1/20 0.37
MAPT P10636 2/20 0.36
GLA P06280 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4154736 0.96 NQO2 (0.46) NQO2DYRK1ACTNNB1WNT3ANPC1
SCHEMBL9375884 0.80 NPC1 (0.46) DYRK1ANPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL11781360 0.79 CYP2A6 (0.41) DYRK1ACTNNB1WNT3ANPC1RAB9A
SCHEMBL29521347 0.79 DYRK1A (0.47) DYRK1AALDH1A1CHRNB2CHRNA4MEN1
SCHEMBL24155753 0.79 CYP2A6 (0.41) DYRK1ANPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL941915 0.78 CHRNB2 (0.48) DYRK1ACTNNB1WNT3ANPC1RAB9A
SCHEMBL6119475 0.76 CHRNB2 (0.47) DYRK1ACTNNB1WNT3ANPC1RAB9A
Naphthalene SCHEMBL4374240 0.76 MAPT (0.43) NQO2DYRK1ACTNNB1WNT3ANPC1
Naphthalene SCHEMBL1068711 0.76 MAPT (0.43) NQO2DYRK1ACTNNB1WNT3ANPC1
SCHEMBL4137601 0.75 DYRK1A (0.42) DYRK1ACTNNB1WNT3ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 460 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6197968-B1 STORAGE STABILITY; COLORLESS AFTER SOLUTION TREATMENT FUJI PHOTO FILM CO., LTD. (JP) 2001-03-06 US claimed
EP-0278509-B1 Silver halide photographic emulsion FUJI PHOTO FILM CO LTD (JP) 1996-01-24 EP claimed
EP-0271260-B1 Supersensitization of silver halide emulsions MINNESOTA MINING & MFG (US) 1995-01-04 EP claimed
EP-0301508-B1 Method for producing a silver halide photographic emulsion FUJI PHOTO FILM CO LTD (JP) 1994-03-23 EP claimed
US-5041366-A Sensitized with mixture of symmetrical and asymmetrical carbocyanine dyes; storage stability KONICA CORPORATION (JP) 1991-08-20 US claimed
US-4970141-A ELEVATED SPECTRAL SENSITIVITY IN GREEN WAVELENGTH REGION FUJI PHOTO FILM CO., LTD. (JP) 1990-11-13 US claimed
US-4873184-A ADDITION OF A METAL COMPLEXING AGENT TO THE EMULSION; HIGH SPEED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-10-10 US claimed
EP-0301508-A2 Method for producing a silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JP) 1989-02-01 EP claimed
EP-0278509-A2 Silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JP) 1988-08-17 EP claimed
EP-0271260-A2 Supersensitization of silver halide emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-15 EP claimed
US-3953215-A X-RAY FILM FUJI PHOTO FILM CO., LTD. (JA) 1976-04-27 US claimed
JP-2162342-A None JP disclosed
US-11795163-B2 Compound for inhibiting nicotinamide phosphoribosyltransferase and composition containing same CHECKMATE THERAPEUTICS INC. 2023-10-24 US disclosed
US-11078195-B2 Compound for inhibiting nicotinamide phosphoribosyltransferase and composition containing same CHECKMATE THERAPEUTICS INC. 2021-08-03 US disclosed
US-20210171513-A1 NOVEL COMPOUND FOR INHIBITING NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE AND COMPOSITION CONTAINING SAME CHECKMATE THERAPEUTICS INC. (KR) 2021-06-10 US disclosed
US-3976493-A CYANINE DYES POLAROID CORPORATION (US) 1976-08-24 US disclosed
US-3955996-A Method for spectrally sensitizing photographic light-sensitive emulsion FUJI PHOTO FILM CO., LTD. (JA) 1976-05-11 US disclosed
US-3953215-A X-RAY FILM FUJI PHOTO FILM CO., LTD. (JA) 1976-04-27 US disclosed
US-3951666-A CYANINE AND MEROCYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-04-20 US disclosed
US-3933507-A LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER AGFA-GEVAERT, A.G. (DT) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11078195-B2 Compound for inhibiting nicotinamide phosphoribosyltransferase and composition containing same NAMPT, NAPRT, NNT NQO2 185/4885DYRK1A 4630/4885CTNNB1 4151/4885
US-20210171513-A1 NOVEL COMPOUND FOR INHIBITING NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE AND COMPOSITION CONTAINING SAME NAMPT, NAPRT, NNMT NQO2 232/4885DYRK1A 4549/4885CTNNB1 3999/4885
US-11795163-B2 Compound for inhibiting nicotinamide phosphoribosyltransferase and composition containing same NAMPT, NAPRT, NNT NQO2 185/4885DYRK1A 4630/4885CTNNB1 4151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.