SCHEMBL3948636

SCHEMBL3948636

CCOC(=O)C1CCCCC1Oc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.46
PKM P14618 1/20 0.46
TSHR P16473 4/20 0.45
ALDH1A1 P00352 2/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 1/20 0.41
CCR8 P51685 1/20 0.41
POLB P06746 1/20 0.41
THRB P10828 1/20 0.41
MAPK1 P28482 1/20 0.41
ATM Q13315 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5006422 0.86 ALDH1A1 (0.44) ALDH1A1NPC1MEN1KMT2AKDM4E
SCHEMBL5248361 0.86 TAS1R3 (0.43) MAPTPKMTSHRALDH1A1NPC1
SCHEMBL28278031 0.81 KCNH2 (0.55) MAPTPKMMEN1KMT2AATM
SCHEMBL12438413 0.79 MAPT (0.48) MAPTPKMTSHRALDH1A1NPC1
SCHEMBL5006420 0.79 ALDH1A1 (0.46) MAPTPKMALDH1A1NPC1MEN1
SCHEMBL1723300 0.78 TSHR (0.45) MAPTPKMTSHRALDH1A1MEN1
SCHEMBL28277997 0.78 KCNH2 (0.55) MAPTPKM
SCHEMBL1723301 0.78 TSHR (0.45) MAPTPKMTSHRALDH1A1MEN1
SCHEMBL10812447 0.77 MAPT (0.65) MAPTPKMTSHRALDH1A1MEN1
SCHEMBL20924718 0.77 TSHR (0.52) MAPTPKMTSHRALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090280977-A1 PROCESS FOR PREPARING CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L (IT) 2009-11-12 US disclosed
EP-2051999-A1 PROCESS FOR PREPARING CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2009-04-29 EP disclosed
WO-2008019802-A1 PROCESS FOR PREPARING CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (DE) 2008-02-21 WO disclosed
CN-1190441-C Phosphine sulfide preparing process and use thereof MITSUI CHEMICALS INC (JP) 2005-02-23 CN disclosed
EP-0790260-B1 Solid catalyst components for polymerization JAPAN POLYOLEFINS CO LTD (JP) 2002-11-06 EP disclosed
EP-0849291-B1 Catalyst for olefin polymerization and method for preparing polyolefins JAPAN POLYOLEFINS CO LTD (JP) 2002-02-13 EP disclosed
US-6271167-B1 TRIMETHOXYSILANE COMPOUND JAPAN POLYOLEFINS CO., LTD. (JP) 2001-08-07 US disclosed
EP-0717053-B1 Catalyst for olefin polymerization and process for producing polyolefin using the same JAPAN POLYOLEFINS CO LTD (JP) 2001-03-14 EP disclosed
US-6096844-A COMPRISING A TITANIUM COMPOUND, A MAGNESIUM COMPOUND, AND A HALOGEN COMPOUND, AN ORGANOALUMINUM COMPOUND, AN ORGANOSILICON COMPOUND JAPAN POLYOLEFINS CO., LTD. (JP) 2000-08-01 US disclosed
US-6063727-A CATALYSTS WHICH ENABLE EFFICIENT PRODUCTION OF POLYOLEFINS HAVING LOW MOLECULAR WEIGHT, BROAD MOLECULAR WEIGHT DISTRIBUTION, HIGH STEREOREGULARITY JAPAN POLYOLEFINS CO., LTD. (JP) 2000-05-16 US disclosed
EP-0790260-A1 Solid catalyst components for polymerization JAPAN POLYOLEFINS CO., LTD. (JP) 1997-08-20 EP disclosed
EP-0640624-B1 Catalyst for polymerization of olefin and process for the preparation of olefin polymer SHOWA DENKO KK (JP) 1997-06-18 EP disclosed
EP-0717053-A2 Catalyst for olefin polymerization and process for producing polyolefin using the same JAPAN POLYOLEFINS CO., LTD. (JP) 1996-06-19 EP disclosed
US-5476825-A Consists of magnesium, titanium and halogen compounds, an organoaluminum compound, a reaction product of organoaluminum or organoboron compound with organosilicon compound SHOWA DENKO K.K. (JP) 1995-12-19 US disclosed
EP-0383346-B1 Catalyst, process for its preparation and process for polymerization of olefins using this catalyst SHOWA DENKO KK (JP) 1995-05-03 EP disclosed
US-5407883-A Containing magnesium, titanium, aluminum and silicon compounds including polymeric aluminum and alumoxanes SHOWA DENKO K.K. (JP) 1995-04-18 US disclosed
EP-0640624-A1 Catalyst for polymerization of olefin and process for the preparation of olefin polymer SHOWA DENKO KABUSHIKI KAISHA (JP) 1995-03-01 EP disclosed
EP-0578473-A1 Catalyst for polymerization of olefin and process for producing olefin polymer SHOWA DENKO KABUSHIKI KAISHA (JP) 1994-01-12 EP disclosed
US-5041403-A Magnesium, titanium, halogen, ester compound, and organic aluminum compound SHOWA DENKO K.K. (JP) 1991-08-20 US disclosed
EP-0383346-A2 Catalyst, process for its preparation and process for polymerization of olefins using this catalyst SHOWA DENKO KABUSHIKI KAISHA (JP) 1990-08-22 EP disclosed