Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CHKA | P35790 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947989 | 0.98 | ALDH1A1 (0.56) | ALDH1A1CA2CHKAKMT2AMEN1 | |
| SCHEMBL3949742 | 0.98 | ALDH1A1 (0.56) | ALDH1A1CA2CHKAKMT2AMEN1 | |
| SCHEMBL3948863 | 0.86 | ALDH1A1 (0.48) | ALDH1A1CA2CHKAKMT2AMEN1 | |
| SCHEMBL3954336 | 0.86 | ALDH1A1 (0.48) | ALDH1A1CA2CHKAKMT2AMEN1 | |
| SCHEMBL3948085 | 0.84 | ALDH1A1 (0.52) | ALDH1A1CA2CHKAKMT2AMEN1 | |
| SCHEMBL3954031 | 0.84 | ALDH1A1 (0.52) | ALDH1A1CA2CHKAKMT2AMEN1 | |
| SCHEMBL3947404 | 0.84 | ALDH1A1 (0.52) | ALDH1A1CA2CHKAKMT2AMEN1 | |
| SCHEMBL3954447 | 0.84 | ALDH1A1 (0.52) | ALDH1A1CA2CHKAKMT2AMEN1 | |
| SCHEMBL413020 | 0.74 | ALDH1A1 (0.87) | ALDH1A1CA2CHKAKMT2AMEN1 | |
| SCHEMBL3954333 | 0.74 | ALDH1A1 (0.87) | ALDH1A1CA2CHKAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051974-A1 | TETRAHYDROBENZOTHIOPHENE DERIVATIVES | 4SC AG (DE) | 2009-04-29 | — | — | EP | claimed |
| WO-2008020045-A1 | TETRAHYDROBENZOTHIOPHENE DERIVATIVES | 4SC AG (DE) | 2008-02-21 | — | — | WO | claimed |
| EP-2051974-A1 | TETRAHYDROBENZOTHIOPHENE DERIVATIVES | 4SC AG (DE) | 2009-04-29 | — | — | EP | disclosed |
| WO-2008020045-A1 | TETRAHYDROBENZOTHIOPHENE DERIVATIVES | 4SC AG (DE) | 2008-02-21 | — | — | WO | disclosed |