Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.87 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | CHKA | P35790 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3954333 | 1.00 | ALDH1A1 (0.87) | ALDH1A1CA2CHKAMEN1KMT2A | |
| SCHEMBL3947402 | 0.96 | ALDH1A1 (0.93) | ALDH1A1CA2CHKAMEN1KMT2A | |
| SCHEMBL733597 | 0.96 | ALDH1A1 (0.93) | ALDH1A1CA2CHKAMEN1KMT2A | |
| SCHEMBL446167 | 0.96 | ALDH1A1 (0.93) | ALDH1A1CA2CHKAMEN1KMT2A | |
| SCHEMBL3948691 | 0.96 | ALDH1A1 (0.88) | ALDH1A1CA2CHKAMEN1KMT2A | |
| SCHEMBL3947407 | 0.96 | ALDH1A1 (0.93) | ALDH1A1CA2CHKAMEN1KMT2A | |
| SCHEMBL2323473 | 0.96 | ALDH1A1 (0.93) | ALDH1A1CA2CHKAMEN1KMT2A | |
| SCHEMBL3948090 | 0.96 | ALDH1A1 (0.93) | ALDH1A1CA2CHKAMEN1KMT2A | |
| SCHEMBL3948084 | 0.96 | ALDH1A1 (0.93) | ALDH1A1CA2CHKAMEN1KMT2A | |
| SCHEMBL3948862 | 0.96 | ALDH1A1 (0.93) | ALDH1A1CA2CHKAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1314 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3261639-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS AS SERINE PROTEASE INHIBITORS | VERSEON INT CORPORATION (US) | 2022-08-24 | — | — | EP | claimed |
| CN-113521079-A | Use of IRAK4 inhibitors for the treatment of ALI/ARDS | 上海领泰生物医药科技有限公司 | 2021-10-22 | — | — | CN | claimed |
| CN-110982268-A | Polyether sulfone film for clothing | 昆山华阳新材料股份有限公司 | 2020-04-10 | — | — | CN | claimed |
| CN-105492439-B | Substituted dicyclic compound as bromine structural domain inhibitor | 齐尼思表观遗传学有限公司 | 2019-11-22 | — | — | CN | claimed |
| CN-106715422-B | Indene derivative, preparation method and the pharmaceutical composition for being used to prevent or treat retinal disease comprising it as active constituent | 忠南大学校产学协力团 | 2019-11-19 | — | — | CN | claimed |
| CN-110402947-A | A kind of Hexythiazox and pyridalyl mixed insecticide preparation | LYU LIANYOU | 2019-11-05 | — | — | CN | claimed |
| CN-110343101-A | For treating the estrogen receptor degradation agent of breast cancer | 深圳福沃药业有限公司 | 2019-10-18 | — | — | CN | claimed |
| CN-110313486-A | A kind of kasugarnycin and prochloraz nantokite mixed insecticide preparation | 厉俊凡 | 2019-10-11 | — | — | CN | claimed |
| CN-106795179-B | Kinase inhibitor | 锦州奥鸿药业有限责任公司 | 2019-09-17 | — | — | CN | claimed |
| CN-106795165-B | Imidazopyridazine compounds | 辉瑞公司 | 2019-09-10 | — | — | CN | claimed |
| CN-1784967-A | Herbicide used in rape field, prepn. method and use thereof | SHANGHAI INST ORGANIC CHEM (CN) | 2006-06-14 | — | — | CN | claimed |
| CN-1696201-A | Thermoplastic polyamide moulded compositions | EMS CHEMIE AG (CH) | 2005-11-16 | — | — | CN | claimed |
| CN-1582417-A | Coating film forming agent for pattern miniaturization and method for forming fine pattern using the same | TOKYO OHKA KOGYO CO LTD (JP) | 2005-02-16 | — | — | CN | claimed |
| CN-1150278-C | Polyarylene sulfide resin composition | ��Ԩ��ѧ��ҵ��ʽ���� | 2004-05-19 | — | — | CN | claimed |
| CN-1468095-A | Colloidal suspension of submicronic particles for carrying hydrophilic active principles (insulin) and method for preparing same | ÷ | 2004-01-14 | — | — | CN | claimed |
| CN-1453647-A | Film opaque for lithographic printing plate | FUJI PHOTO FILM CO LTD (JP) | 2003-11-05 | — | — | CN | claimed |
| CN-1244886-A | Polyarylene sulfide resin composition | KUREHA CHEMICAL IND CO LTD (JP) | 2000-02-16 | — | — | CN | claimed |
| CN-1241942-A | N-linked ureas and carbamates of heterocyclic thioesters | GUILFORD PHARM INC (US) | 2000-01-19 | — | — | CN | claimed |
| US-5618951-A | REACTING A CHLORODIFLUOROACETATE WITH A HALOSILANE USING AN UREA SILVENT AND A REDUCING AGENT | ELI LILLY AND COMPANY (US) | 1997-04-08 | — | — | US | claimed |
| CN-1060463-A | The production method of amidinothiourea | SUEDDEUTSCHE KALKSTICKSTOFF (DE) | 1992-04-22 | — | — | CN | claimed |