Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2440693 | 1.00 | REN (0.41) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL2440694 | 1.00 | REN (0.41) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL3946910 | 0.91 | REN (0.41) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL3951966 | 0.90 | REN (0.40) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL3944950 | 0.87 | REN (0.40) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL6854827 | 0.87 | REN (0.40) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL13206701 | 0.84 | REN (0.39) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL13337107 | 0.84 | REN (0.39) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL8196536 | 0.84 | REN (0.39) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL6853878 | 0.83 | REN (0.41) | RENHTR1AADRA1DHTR2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010480-A1 | METHOD FOR THE PRODUCTION OF 8-ARYL-OCTANOYL DERIVATIVES | Reuter Chemische Apparatebau KG (DE) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007118681-A1 | METHOD FOR THE PRODUCTION OF 8-ARYL-OCTANOYL DERIVATIVES | REUTER CHEMISCHER APPARATEBAU KG (DE) | 2007-10-25 | — | — | WO | disclosed |