Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13206687 | 0.84 | REN (0.46) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL3946910 | 0.83 | REN (0.41) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL3951966 | 0.83 | REN (0.40) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL2440693 | 0.83 | REN (0.41) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL3948909 | 0.83 | REN (0.41) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL2440694 | 0.83 | REN (0.41) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL6854710 | 0.80 | REN (0.44) | REN | |
| SCHEMBL3944950 | 0.80 | REN (0.40) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL6854827 | 0.80 | REN (0.40) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL2428903 | 0.78 | REN (0.40) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011064790-A1 | A NOVEL PROCESS FOR MAKING ALISKIREN, ITS NOVEL INTERMEDIATES AND CERTAIN NOVEL COMPOUNDS | Avra Laboratories Pvt. Ltd (IN) | 2011-06-03 | — | — | WO | disclosed |