Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27669794 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2DRD4PDE1BFKBP1ATSHR | |
| SCHEMBL3509984 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2DRD4PDE1BALDH1A1GAA | |
| SCHEMBL1458786 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2DRD4PDE1BALDH1A1GAA | |
| SCHEMBL696684 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2DRD4PDE1BALDH1A1GAA | |
| SCHEMBL20637905 | 0.81 | LTA4H (0.41) | SMN1; SMN2FKBP1ATSHRALDH1A1SIGMAR1 | |
| SCHEMBL20637907 | 0.81 | LTA4H (0.41) | SMN1; SMN2FKBP1ATSHRALDH1A1SIGMAR1 | |
| SCHEMBL2443609 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2DRD4PDE1BFKBP1ATSHR | |
| SCHEMBL1177324 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2DRD4PDE1BFKBP1ATSHR | |
| SCHEMBL1176886 | 0.78 | SIGMAR1 (0.57) | SMN1; SMN2FKBP1ATSHRHIF1AEPAS1 | |
| SCHEMBL1177023 | 0.78 | SIGMAR1 (0.57) | SMN1; SMN2FKBP1ATSHRHIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016410-A2 | CHEMICAL COMPOUNDS 831 | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | WO | disclosed |