Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3950231 | 0.86 | ALDH1A1 (0.39) | KMT2AMEN1ALDH1A1CTSLCTSS | |
| SCHEMBL3949447 | 0.85 | CTSL (0.41) | KMT2AMEN1ALDH1A1CTSLCTSS | |
| SCHEMBL3951319 | 0.84 | CTSL (0.44) | KMT2AMEN1ALDH1A1CTSLCTSS | |
| SCHEMBL3950858 | 0.83 | CTSL (0.41) | KMT2AMEN1ALDH1A1CTSLCTSS | |
| SCHEMBL3954832 | 0.83 | CTSL (0.39) | KMT2AMEN1ALDH1A1CTSLCTSS | |
| SCHEMBL3955669 | 0.82 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1CTSLCTSS | |
| SCHEMBL3954226 | 0.81 | CTSL (0.40) | KMT2AMEN1ALDH1A1CTSLCTSS | |
| SCHEMBL3949052 | 0.81 | CTSL (0.46) | KMT2AMEN1ALDH1A1CTSLCTSS | |
| SCHEMBL3948515 | 0.80 | CTSL (0.45) | KMT2AMEN1ALDH1A1CTSLCTSS | |
| SCHEMBL3944081 | 0.80 | CTSL (0.39) | KMT2AMEN1ALDH1A1CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026197-A1 | NOVEL CATHEPSIN C INHIBITORS AND THEIR USE | GLAXO GROUP LIMITED (GB) | 2009-02-26 | — | — | WO | disclosed |