Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1483919 | 0.91 | AR (0.53) | ARKCNQ3KCNQ2L3MBTL1FGFR1 | |
| SCHEMBL1483214 | 0.80 | KCNQ3 (0.52) | ARKCNQ3KCNQ2SMN1; SMN2IDO1 | |
| SCHEMBL1483167 | 0.78 | KCNQ3 (0.53) | ARKCNQ3KCNQ2IDO1SCN10A | |
| SCHEMBL1483215 | 0.73 | ALDH1A1 (0.48) | ARKCNQ3KCNQ2SMN1; SMN2HDAC3 | |
| SCHEMBL19776339 | 0.72 | KCNQ3 (0.56) | ARKCNQ3KCNQ2SCN10ABRAF | |
| SCHEMBL13036452 | 0.72 | AR (0.59) | ARKCNQ3KCNQ2L3MBTL1SMN1; SMN2 | |
| SCHEMBL31680457 | 0.72 | AR (0.59) | ARKCNQ3KCNQ2L3MBTL1SMN1; SMN2 | |
| SCHEMBL20942380 | 0.72 | AR (0.59) | ARKCNQ3KCNQ2SMN1; SMN2SCN10A | |
| SCHEMBL1483561 | 0.72 | MAPT (0.56) | ARKCNQ3KCNQ2L3MBTL1SMN1; SMN2 | |
| SCHEMBL3305812 | 0.71 | AR (0.57) | ARKCNQ3KCNQ2SCN10ABRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019656-A1 | PYRIDYL DERIVATIVES, THEIR PREPARATION AND USE | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2009-02-12 | — | — | WO | disclosed |