SCHEMBL3949773

SCHEMBL3949773

CCP(=O)(OC)c1ccc2oc(-c3ccc(Cl)c(Cl)c3)nc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
UTRN P46939 20/20 1.00
HTR2B P41595 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2245505 0.89 UTRN (1.00) UTRNHTR2B
SCHEMBL15423678 0.85 UTRN (0.81) UTRNHTR2B
SCHEMBL3953925 0.81 UTRN (1.00) UTRNHTR2B
SCHEMBL29411312 0.79 UTRN (1.00) UTRNHTR2B
SCHEMBL2247922 0.73 UTRN (0.70) UTRN
SCHEMBL3944357 0.72 UTRN (0.71) UTRNHTR2B
SCHEMBL24869256 0.71 MAPT (0.70) UTRN
SCHEMBL5049061 0.70 UTRN (0.54) UTRN
SCHEMBL2246803 0.70 MAPT (0.58) UTRN
SCHEMBL3951712 0.70 ESR1 (0.56) UTRN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009021750-A2 TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY SUMMIT CORPORATION PLC (GB) 2009-02-19 WO disclosed