Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 7/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30802521 | 0.86 | KIF11 (0.50) | KIF11CYP3A4CYP2C9KCNH2CYP2C19 | |
| SCHEMBL10520172 | 0.84 | MAPT (0.44) | KIF11CYP3A4CYP2C19HIF1ACYP1A2 | |
| SCHEMBL4955482 | 0.84 | KCNN4 (0.45) | KIF11CYP3A4CYP2C9KCNH2CYP2C19 | |
| SCHEMBL28779165 | 0.83 | CYP3A4 (0.43) | KIF11CYP3A4CYP2C9KCNH2CYP2C19 | |
| SCHEMBL1177684 | 0.82 | HIF1A (0.44) | KIF11CYP3A4CYP2C9KCNH2CYP2C19 | |
| SCHEMBL27726754 | 0.82 | HIF1A (0.44) | KIF11CYP3A4CYP2C9KCNH2CYP2C19 | |
| SCHEMBL2678001 | 0.81 | CYP2C19 (0.48) | KIF11CYP3A4CYP2C9KCNH2CYP2C19 | |
| SCHEMBL1233526 | 0.80 | HIF1A (0.42) | KIF11CYP3A4CYP2C9KCNH2CYP2C19 | |
| SCHEMBL3401876 | 0.80 | OPRM1 (0.48) | KIF11KCNH2CYP2C19HIF1ACYP1A2 | |
| SCHEMBL27759298 | 0.80 | HIF1A (0.42) | KIF11CYP3A4CYP2C9KCNH2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527545-B | Beta-cyclodextrin polyrotaxane with accurate insertion amount, preparation method and application thereof | 北京理工大学 | 2022-05-17 | — | — | CN | claimed |
| CN-113527545-A | Beta-cyclodextrin polyrotaxane with accurate insertion amount, preparation method and application thereof | 北京理工大学 | 2021-10-22 | — | — | CN | claimed |
| CN-103509083-B | A kind of wide spectrum beta-lactamase fluorogenic substrate and its preparation method and application | 王郁生 | 2016-06-08 | — | — | CN | claimed |
| CN-103509083-A | Broad-spectrum beta-lactamase fluorescent substrate, and preparation method and application thereof | WANG YUSHENG | 2014-01-15 | — | — | CN | claimed |
| WO-1994024095-A1 | IMMUNOSUPPRESSIVE AGENTS | ABBOTT LABORATORIES (US) | 1994-10-27 | — | — | WO | claimed |
| CN-110546155-B | Process for producing peptide | 浜理药品工业株式会社 | 2023-06-23 | — | — | CN | disclosed |
| WO-2022138891-A1 | METHOD FOR PRODUCING PEPTIDE COMPOUND CONTAINING N-SUBSTITUTED-AMINO ACID RESIDUE | 中外製薬株式会社 | 2022-06-30 | — | — | WO | disclosed |
| CN-108271357-B | Molecular constructs for treatment of transplant rejection | 免疫功坊股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-113527545-B | Beta-cyclodextrin polyrotaxane with accurate insertion amount, preparation method and application thereof | 北京理工大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-113527545-A | Beta-cyclodextrin polyrotaxane with accurate insertion amount, preparation method and application thereof | 北京理工大学 | 2021-10-22 | — | — | CN | disclosed |
| WO-2021127176-A1 | UNNATURAL AMINO ACIDS AND USES THEREOF | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2021-06-24 | — | — | WO | disclosed |
| CN-108271357-A | Molecular constructs for treatment of transplant rejection | 免疫功坊股份有限公司 | 2018-07-10 | — | — | CN | disclosed |
| CN-104350096-B | Thermoplastic melt-mixed composition with amino acid heat stabilizer | 纳幕尔杜邦公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-103509083-B | A kind of wide spectrum beta-lactamase fluorogenic substrate and its preparation method and application | 王郁生 | 2016-06-08 | — | — | CN | disclosed |
| CN-103509083-A | Broad-spectrum beta-lactamase fluorescent substrate, and preparation method and application thereof | WANG YUSHENG | 2014-01-15 | — | — | CN | disclosed |
| WO-2009027085-A1 | PROCESS FOR CARRYING OUT A CHEMICAL REACTION IN A CELL | CHROMATIDE LTD (GB) | 2009-03-05 | — | — | WO | disclosed |
| WO-1994024095-A1 | IMMUNOSUPPRESSIVE AGENTS | ABBOTT LABORATORIES (US) | 1994-10-27 | — | — | WO | disclosed |
| EP-0284966-B1 | Processes for the preparation of benzo (chalcogeno)[4,3,2-CD] indazoles | WARNER-LAMBERT COMPANY (US) | 1992-01-02 | — | — | EP | disclosed |
| US-4806654-A | Processes for the preparation of benzo(chalcogeno)(4,3,2-cd)indazoles and intermediates thereof | WARNER-LAMBERT COMPANY (US) | 1989-02-21 | — | — | US | disclosed |
| EP-0284966-A1 | Processes for the preparation of benzo (chalcogeno)[4,3,2-CD] indazoles | WARNER-LAMBERT COMPANY (US) | 1988-10-05 | — | — | EP | disclosed |