Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.86 |
| ▸ | PPARD | Q03181 | 4/20 | 0.86 |
| ▸ | PPARA | Q07869 | 4/20 | 0.86 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.68 |
| ▸ | NPC1 | O15118 | 10/20 | 0.68 |
| ▸ | RAB9A | P51151 | 9/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.68 |
| ▸ | MAPT | P10636 | 8/20 | 0.68 |
| ▸ | HPGD | P15428 | 7/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.68 |
| ▸ | LMNA | P02545 | 5/20 | 0.68 |
| ▸ | TP53 | P04637 | 4/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.68 |
| ▸ | BLM | P54132 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.68 |
| ▸ | MAOA | P21397 | 2/20 | 0.68 |
| ▸ | MAOB | P27338 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pseudobaptogenin SCHEMBL73016 | 0.92 | PPARG (1.00) | PPARGPPARDPPARAKDM4ENPC1 | |
| Daidzein SCHEMBL29374778 | 0.82 | KDM4E (1.00) | PPARGPPARDPPARAKDM4ENPC1 | |
| Daidzein SCHEMBL19814 | 0.82 | KDM4E (1.00) | PPARGPPARDPPARAKDM4ENPC1 | |
| Daidzein SCHEMBL21114371 | 0.82 | KDM4E (1.00) | PPARGPPARDPPARAKDM4ENPC1 | |
| SCHEMBL5267997 | 0.81 | NPC1 (0.61) | PPARGPPARDPPARAKDM4ENPC1 | |
| SCHEMBL30082665 | 0.81 | MAPT (1.00) | PPARGPPARDPPARAKDM4ENPC1 | |
| SCHEMBL12721801 | 0.81 | MAPT (1.00) | PPARGPPARDPPARAKDM4ENPC1 | |
| SCHEMBL29884186 | 0.80 | MIF (0.84) | PPARGPPARDPPARAKDM4ENPC1 | |
| SCHEMBL29482679 | 0.80 | XDH (1.00) | PPARGPPARDPPARAKDM4ENPC1 | |
| SCHEMBL73012 | 0.80 | XDH (1.00) | PPARGPPARDPPARAKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026657-A1 | FLAVONOID PPAR AGONISTS | THE UNIVERSITY OF SYDNEY (AU) | 2009-03-05 | — | — | WO | disclosed |
| WO-2009026657-A1 | FLAVONOID PPAR AGONISTS | THE UNIVERSITY OF SYDNEY (AU) | 2009-03-05 | — | — | WO | disclosed |