SCHEMBL73012

SCHEMBL73012

O=c1c(-c2ccc(O)c(O)c2)coc2cc(O)ccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 3/20 1.00
MIF P14174 2/20 1.00
KDM4E B2RXH2 8/20 0.78
ALDH1A1 P00352 6/20 0.78
HSD17B10 Q99714 6/20 0.78
NPC1 O15118 5/20 0.78
RAB9A P51151 5/20 0.78
MAPT P10636 5/20 0.78
HPGD P15428 5/20 0.78
SMN1; SMN2 Q16637 4/20 0.78
TP53 P04637 4/20 0.78
CYP3A4 P08684 3/20 0.78
CYP2C9 P11712 3/20 0.78
HDAC6 Q9UBN7 3/20 0.78
CYP2D6 P10635 2/20 0.78
MAOA P21397 2/20 0.78
MAOB P27338 2/20 0.78
CYP2C19 P33261 2/20 0.78
LMNA P02545 2/20 0.78
PKM P14618 2/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29482686 1.00 XDH (1.00) XDHMIFKDM4EALDH1A1HSD17B10
SCHEMBL29482679 1.00 XDH (1.00) XDHMIFKDM4EALDH1A1HSD17B10
SCHEMBL29392289 1.00 XDH (1.00) XDHMIFKDM4EALDH1A1HSD17B10
SCHEMBL29884186 0.91 MIF (0.84) XDHMIFKDM4EALDH1A1HSD17B10
Daidzein SCHEMBL29374778 0.88 KDM4E (1.00) XDHMIFKDM4EALDH1A1HSD17B10
Daidzein SCHEMBL21114371 0.88 KDM4E (1.00) XDHMIFKDM4EALDH1A1HSD17B10
Daidzein SCHEMBL19814 0.88 KDM4E (1.00) XDHMIFKDM4EALDH1A1HSD17B10
SCHEMBL8161550 0.87 XDH (0.78) XDHMIFKDM4EALDH1A1HSD17B10
SCHEMBL555129 0.87 XDH (0.76) XDHMIFKDM4EALDH1A1HSD17B10
SCHEMBL29929481 0.87 XDH (0.76) XDHMIFKDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 298 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2603098-B1 METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER FIRMENICH INCORPORATED (US) 2025-08-06 EP claimed
US-12163004-B2 Polymer composites WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2024-12-10 US claimed
CN-115975963-B Method for synthesizing hydroxylated flavone compound by using escherichia coli P450 enzyme whole cell catalysis and application thereof 江南大学 2023-10-03 CN claimed
CN-115975963-A Method for synthesizing hydroxylated flavone compound by using escherichia coli P450 enzyme whole-cell catalysis and application 江南大学 2023-04-18 CN claimed
CN-111574489-B Synthetic method of 3',4', 7-trihydroxyisoflavone 中国人民解放军联勤保障部队第九〇四医院 2022-04-29 CN claimed
US-10695283-B2 Extract of Greyia radlkoferi and use thereof UNIVERSITY OF PRETORIA (ZA) 2020-06-30 US claimed
US-20190200602-A1 Platelet Additive Solution Having a Beta-Galactosidase Inhibitor VELICO MEDICAL, INC. (US) 2019-07-04 US claimed
US-20190203175-A1 Platelet Protection Solution Having a Beta-Galactosidase Inhibitor VELICO MEDICAL, INC. (US) 2019-07-04 US claimed
CN-104582713-B Grignard family feijie extract and application thereof 比勒陀利亚大学 2019-05-28 CN claimed
US-10271541-B2 Platelet additive solution having a beta-galactosidase inhibitor VELICO MEDICAL, INC (US) 2019-04-30 US claimed
US-20120016019-A1 PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING CANCER LEE GEE-HWOON (KR) 2012-01-19 US claimed
US-20120016017-A1 PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING CANCER LEE GEE-HWOON (KR) 2012-01-19 US claimed
US-20110224291-A1 SKIN EXTERNAL COMPOSITION FOR INHIBITING EPIDERMAL HYPERPROLIFERATION AND ALLEVIATING INFLAMMATORY SKIN DISEASES CONTAINING ORTHODIHYDROXYISOFLAVONE DERIVATIVES AMOREPACIFIC CORPORATION (KR) 2011-09-15 US claimed
EP-2361089-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ALTERED -SYNUCLEIN FUNCTION Parkinson's Institute (US) 2011-08-31 EP claimed
EP-2349254-A2 SKIN EXTERNAL COMPOSITION FOR INHIBITING EPIDERMAL HYPERPROLIFERATION AND ALLEVIATING INFLAMMATORY SKIN DISEASES CONTAINING ORTHO-DIHYDROXYISOFLAVONE DERIVATIVES Amorepacific Corporation (KR) 2011-08-03 EP claimed
US-20110033904-A1 METHOD FOR PREPARING ORTHODIHYDROXYISOFLAVONES USING A BIOTRANSFORMATION SYSTEM AMOREPACIFIC CORPORATION (KP) 2011-02-10 US claimed
US-20100167286-A1 Pluripotent cell lines and methods of use thereof PARKINSON'S INSTITUTE (US) 2010-07-01 US claimed
WO-2010058936-A2 SKIN EXTERNAL COMPOSITION FOR INHIBITING EPIDERMAL HYPERPROLIFERATION AND ALLEVIATING INFLAMMATORY SKIN DISEASES CONTAINING ORTHO-DIHYDROXYISOFLAVONE DERIVATIVES AMOREPACIFIC CORPORATION (KR) 2010-05-27 WO claimed
WO-2010056413-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ALTERED α-SYNUCLEIN FUNCTION PARKINSON'S INSTITUTE (US) 2010-05-20 WO claimed
WO-2010008486-A2 PLURIPOTENT CELL LINES AND METHODS OF USE THEREOF PARKINSONS INSTITUTE (US) 2010-01-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120016019-A1 PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING CANCER H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, H1-5, KRAS XDH 2193/4885MIF 4579/4885KDM4E 4070/4885
US-20120016017-A1 PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING CANCER H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, WASHC5, ASAH1 XDH 2755/4885MIF 4256/4885KDM4E 3250/4885
US-20110224291-A1 SKIN EXTERNAL COMPOSITION FOR INHIBITING EPIDERMAL HYPERPROLIFERATION AND ALLEVIATING INFLAMMATORY SKIN DISEASES CONTAINING ORTHODIHYDROXYISOFLAVONE DERIVATIVES DKK1, FZD7, CTNND1 XDH 2812/4885MIF 2317/4885KDM4E 2677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.