Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3950701 | 0.95 | NAMPT (0.36) | ALDH1A1NAMPTGNAO1GNAI3GNAI1 | |
| SCHEMBL3949394 | 0.93 | ALDH1A1 (0.41) | ALDH1A1GNAO1GNAI3GNAI1CHRM2 | |
| SCHEMBL3948276 | 0.92 | ALDH1A1 (0.38) | ALDH1A1NAMPTGNAO1GNAI3GNAI1 | |
| SCHEMBL3950841 | 0.88 | ALDH1A1 (0.39) | ALDH1A1GNAO1GNAI3GNAI1CHRM2 | |
| SCHEMBL3950617 | 0.86 | ALDH1A1 (0.38) | ALDH1A1NAMPTGNAO1GNAI3GNAI1 | |
| SCHEMBL3947870 | 0.86 | ALDH1A1 (0.45) | ALDH1A1GNAO1GNAI3GNAI1GAA | |
| SCHEMBL3949683 | 0.85 | CHRM1 (0.33) | ALDH1A1NAMPTGNAO1DRD4CHRM2 | |
| SCHEMBL3950772 | 0.82 | ALDH1A1 (0.36) | ALDH1A1NAMPTGNAO1DRD4CHRM2 | |
| SCHEMBL3951167 | 0.81 | DRD2 (0.39) | ALDH1A1GNAO1GNAI3GNAI1DRD4 | |
| SCHEMBL3954270 | 0.81 | ALDH1A1 (0.45) | ALDH1A1GNAO1GNAI3GNAI1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009024825-A1 | 2-PYRAZINYLBENZIMIDAZOLE DERIVATIVES AS RECEPTOR TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2009-02-26 | — | — | WO | disclosed |