Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14311224 | 0.83 | MEN1 (0.62) | GAAKDM4EMEN1USP2KMT2A | |
| SCHEMBL5467266 | 0.83 | AKR1C3 (0.56) | GAAKDM4EMEN1USP2KMT2A | |
| SCHEMBL173243 | 0.80 | AKR1C3 (0.55) | GAAKDM4EMEN1USP2KMT2A | |
| SCHEMBL31727764 | 0.80 | AKR1C3 (0.55) | GAAKDM4EMEN1USP2KMT2A | |
| SCHEMBL4847975 | 0.80 | MAPT (0.58) | GAAKDM4EMEN1USP2KMT2A | |
| SCHEMBL39787 | 0.76 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1ATMTDP1 | |
| SCHEMBL31726609 | 0.76 | HNF4A (0.43) | GAAKDM4EMEN1USP2KMT2A | |
| Vinyl Chloride SCHEMBL28345010 | 0.76 | AKR1C3 (0.50) | GAAKDM4EMEN1USP2KMT2A | |
| SCHEMBL27511884 | 0.76 | AKR1C3 (0.46) | GAAKDM4EMEN1USP2KMT2A | |
| SCHEMBL1941954 | 0.75 | ATM (0.63) | KDM4EMEN1KMT2AALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547445-B2 | Crosslinkable macromers | SURMODICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| WO-2008002852-A2 | CROSSLINKABLE MACROMERS | SURMODICS, INC. (US) | 2008-01-03 | — | — | WO | disclosed |
| US-20060240072-A1 | Side effect reduction of implanted medical devices by coating the surface with a curable mixture or solution of a photoinitiator and a crosslinkable macromer with pendant polymerizable groups; nontoxicity, efficiency, and solubility; drug delivery, cellular immune isolation, tissue repair | SURMODICS, INC. | 2006-10-26 | — | — | US | disclosed |
| US-7094418-B2 | Crosslinkable macromers | SURMODICS, INC. (US) | 2006-08-22 | — | — | US | disclosed |
| US-7087658-B2 | Water-soluble coating agents bearing initiator groups | SURMODICS, INC. (US) | 2006-08-08 | — | — | US | disclosed |
| EP-1593377-A1 | Crosslinkable macromers bearing initiator groups | SurModics, Inc. (US) | 2005-11-09 | — | — | EP | disclosed |
| US-6924370-B2 | Crosslinkable macromers | SURMODICS, INC. (US) | 2005-08-02 | — | — | US | disclosed |
| US-20050136091-A1 | Crosslinkable macromers | Surmodics Coatings, LLC | 2005-06-23 | — | — | US | disclosed |
| EP-1063975-B1 | CROSSLINKABLE MACROMERS BEARING INITIATOR GROUPS | SURMODICS INC (US) | 2005-05-18 | — | — | EP | disclosed |
| US-20040137164-A1 | Water-soluble coating agents bearing initiator groups | SURMODICS, INC. | 2004-07-15 | — | — | US | disclosed |
| EP-1131167-B1 | WATER-SOLUBLE COATING AGENTS BEARING INITIATOR GROUPS AND COATING PROCESS | SURMODICS INC (US) | 2004-07-07 | — | — | EP | disclosed |
| EP-1395301-A1 | CROSSLINKABLE MACROMERS | SurModics, Inc. (US) | 2004-03-10 | — | — | EP | disclosed |
| US-20030031697-A1 | Crosslinkable macromers | Surmodics Coatings, LLC | 2003-02-13 | — | — | US | disclosed |
| WO-2002100453-A1 | CROSSLINKABLE MACROMERS | SURMODICS, INC. (US) | 2002-12-19 | — | — | WO | disclosed |
| US-6410044-B1 | Crosslinkable macromers | SURMODICS, INC. | 2002-06-25 | — | — | US | disclosed |
| US-20020004140-A1 | Water-soluble coating agents bearing initiator groups | Surmodics Coatings, LLC | 2002-01-10 | — | — | US | disclosed |
| EP-1131167-A1 | WATER-SOLUBLE COATING AGENTS BEARING INITIATOR GROUPS AND COATING PROCESS | SurModics, Inc. (US) | 2001-09-12 | — | — | EP | disclosed |
| WO-2001021326-A1 | WATER-SOLUBLE COATING AGENTS BEARING INITIATOR GROUPS AND COATING PROCESS | SURMODICS, INC. (US) | 2001-03-29 | — | — | WO | disclosed |
| US-6156345-A | Crosslinkable macromers bearing initiator groups | SURMODICS, INC. (US) | 2000-12-05 | — | — | US | disclosed |
| US-6007833-A | RESIN MIXTURE HAVING IMPROVED NONTOXICITY, POLYMERIZATION EFFICIENCY, AND SOLUBILITY WHICH FORMS BIODEGRADABLE MATRIX FOR MEDICAL APPLICATION | SURMODICS, INC. (US) | 1999-12-28 | — | — | US | disclosed |