Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.72 |
| ▸ | RAB9A | P51151 | 7/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | ATM | Q13315 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | HPGD | P15428 | 6/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | TP53 | P04637 | 3/20 | 0.66 |
| ▸ | CASP3 | P42574 | 2/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.62 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.62 |
| ▸ | MMP2 | P08253 | 1/20 | 0.62 |
| ▸ | MMP9 | P14780 | 1/20 | 0.62 |
| ▸ | MMP8 | P22894 | 1/20 | 0.62 |
| ▸ | MMP13 | P45452 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Phenylbenzo[D]Oxazole SCHEMBL29819732 | 1.00 | NPC1 (0.72) | NPC1RAB9AMEN1KMT2AATM | |
| 2-Phenylbenzo[D]Oxazole SCHEMBL27567766 | 1.00 | NPC1 (0.72) | NPC1RAB9AMEN1KMT2AATM | |
| 2-Phenylbenzo[D]Oxazole SCHEMBL31738605 | 1.00 | NPC1 (0.72) | NPC1RAB9AMEN1KMT2AATM | |
| 2-Phenylbenzo[D]Oxazole SCHEMBL2458370 | 1.00 | NPC1 (0.72) | NPC1RAB9AMEN1KMT2AATM | |
| 2-Phenylbenzo[D]Oxazole SCHEMBL127448 | 1.00 | NPC1 (0.72) | NPC1RAB9AMEN1KMT2AATM | |
| 2-Phenylbenzo[D]Oxazole SCHEMBL29767802 | 1.00 | NPC1 (0.72) | NPC1RAB9AMEN1KMT2AATM | |
| 2-Phenylbenzo[D]Oxazole SCHEMBL29083041 | 0.98 | NPC1 (0.70) | NPC1RAB9AMEN1KMT2AATM | |
| 2-Phenylbenzo[D]Oxazole SCHEMBL10670878 | 0.98 | NPC1 (0.70) | NPC1RAB9AMEN1KMT2AATM | |
| 2-Phenylbenzo[D]Oxazole SCHEMBL30022108 | 0.98 | NPC1 (0.70) | NPC1RAB9AMEN1KMT2AATM | |
| 2-Phenylbenzo[D]Oxazole SCHEMBL29986166 | 0.98 | NPC1 (0.70) | NPC1RAB9AMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2278637-B2 | Complexes of form L2MX | UNIV PRINCETON (US) | 2021-06-09 | — | — | EP | disclosed |
| US-10629827-B2 | Organometallic complexes as phosphorescent emitters in organic LEDs | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2020-04-21 | — | — | US | disclosed |
| EP-1933395-B2 | Complexes of form L2IrX | UNIV PRINCETON (US) | 2019-08-07 | — | — | EP | disclosed |
| EP-2610887-B1 | Organic light emitting devices for illumination | UNIVERSAL DISPLAY CORP (US) | 2019-04-17 | — | — | EP | disclosed |
| EP-3379591-A1 | COMPLEXES OF FORM L2MX | The Trustees of Princeton University (US) | 2018-09-26 | — | — | EP | disclosed |
| EP-2911211-B1 | COMPLEXES OF FORM L2MX | UNIV PRINCETON (US) | 2018-05-02 | — | — | EP | disclosed |
| US-20170301869-A9 | ORGANOMETALLIC COMPLEXES AS PHOSPHORESCENT EMITTERS IN ORGANIC LEDS | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2017-10-19 | — | — | US | disclosed |
| EP-1252803-B2 | COMPLEXES OF FORM L2MX AS PHOSPHORESCENT DOPANTS FOR ORGANIC LEDS | UNIV PRINCETON (US) | 2015-09-02 | — | — | EP | disclosed |
| EP-2911211-A1 | COMPLEXES OF FORM L2MX | The Trustees of Princeton University (US) | 2015-08-26 | — | — | EP | disclosed |
| EP-2278637-B1 | Complexes of form L2MX | UNIV PRINCETON (US) | 2015-02-25 | — | — | EP | disclosed |
| EP-1576854-A2 | ORGANIC LIGHT EMITTING DEVICES FOR ILLUMINATION | Universal Display Corporation (US) | 2005-09-21 | — | — | EP | disclosed |
| US-6902830-B2 | Organometallic complexes as phosphorescent emitters in organic LEDs | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2005-06-07 | — | — | US | disclosed |
| US-20040262576-A1 | Organometallic complexes as phosphorescent emitters in organic LEDs | THOMPSON MARK E (US) | 2004-12-30 | — | — | US | disclosed |
| US-6830828-B2 | Combining bridged dimer with a Bronsted acid to make an organometallic complex containing monoanionic, didentate ligands, with a metal which forms octahedral complexes | THE TRUSTEES OF PRINCETON UNIVERSITY | 2004-12-14 | — | — | US | disclosed |
| WO-2004017678-A2 | ORGANIC LIGHT EMITTING DEVICES FOR ILLUMINATION | UNIVERSAL DISPLAY CORPORATION (US) | 2004-02-26 | — | — | WO | disclosed |
| EP-1252803-A4 | COMPLEXES OF FORM L 2?MX AS PHOSPHORESCENT DOPANTS FOR ORGANIC LEDS | UNIV PRINCETON (US) | 2003-04-16 | — | — | EP | disclosed |
| US-20030017361-A1 | Organometallic complexes as phosphorescent emitters in organic LEDs | THOMPSON MARK E (US) | 2003-01-23 | — | — | US | disclosed |
| EP-1252803-A1 | COMPLEXES OF FORM L 2?MX AS PHOSPHORESCENT DOPANTS FOR ORGANIC LEDS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2002-10-30 | — | — | EP | disclosed |
| US-20020034656-A1 | Organometallic complexes as phosphorescent emitters in organic LEDs | THE UNIVERSITY OF SOUTHERN CALIFORNIA | 2002-03-21 | — | — | US | disclosed |
| WO-2001041512-A1 | COMPLEXES OF FORM L2MX AS PHOSPHORESCENT DOPANTS FOR ORGANIC LEDS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2001-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10629827-B2 | Organometallic complexes as phosphorescent emitters in organic LEDs | MLX, L1CAM, POU5F1 | NPC1 4450/4885RAB9A 3330/4885MEN1 2227/4885 |
| US-20170301869-A9 | ORGANOMETALLIC COMPLEXES AS PHOSPHORESCENT EMITTERS IN ORGANIC LEDS | MLX, L1CAM, POU5F1 | NPC1 4450/4885RAB9A 3330/4885MEN1 2227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.