SCHEMBL395142

SCHEMBL395142

Cc1cc(C)c(C)c(N)c1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.47
TSHR P16473 5/20 0.47
CYP3A4 P08684 4/20 0.47
TDP1 Q9NUW8 3/20 0.47
MAPK1 P28482 1/20 0.47
TP53 P04637 1/20 0.47
POLB P06746 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.38
GAA P10253 2/20 0.37
MAPT P10636 1/20 0.37
CD44 P16070 2/20 0.35
CASP1 P29466 1/20 0.35
PIK3CA P42336 1/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
KDM4E B2RXH2 2/20 0.32
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL28821509 0.97 ALDH1A1 (0.45) ALDH1A1TSHRCYP3A4TDP1MAPK1
Hydrochloric Acid SCHEMBL29008323 0.97 ALDH1A1 (0.45) ALDH1A1TSHRCYP3A4TDP1MAPK1
Water SCHEMBL27673190 0.97 ALDH1A1 (0.45) ALDH1A1TSHRCYP3A4TDP1MAPK1
SCHEMBL2131880 0.87 ALDH1A1 (0.50) ALDH1A1TSHRCYP3A4TDP1MAPK1
SCHEMBL5152888 0.84 ALDH1A1 (0.41) ALDH1A1TSHRCYP3A4TDP1MAPK1
SCHEMBL1277356 0.84 ALDH1A1 (0.48) ALDH1A1TSHRCYP3A4TDP1MAPK1
Acetic Acid SCHEMBL28200831 0.84 KDM4E (0.43) ALDH1A1TSHRCYP3A4TDP1MAPK1
Hydrochloric Acid SCHEMBL5177923 0.82 ALDH1A1 (0.46) ALDH1A1TSHRCYP3A4TDP1MAPK1
SCHEMBL3389856 0.80 ALDH1A1 (0.50) ALDH1A1TSHRCYP3A4TDP1MAPK1
SCHEMBL29738345 0.80 ALDH1A1 (0.50) ALDH1A1TSHRCYP3A4TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120192204-A Preparation method of fluoro aromatic hydrocarbon compound 阜新孚隆宝医药科技有限公司 2025-06-24 CN claimed
US-12071388-B2 Full continuous flow synthesis process of fluorine-containing aromatic hydrocarbon compounds Fujian Zhongxin Fluoride Material Gaobao Technology Co., Ltd. (CN) 2024-08-27 US claimed
US-20220204427-A1 FULL CONTINUOUS FLOW SYNTHESIS PROCESS OF FLUORINE-CONTAINING AROMATIC HYDROCARBON COMPOUNDS Fujian Zhongxin Fluoride Material Gaobao Technology Co., Ltd. (CN) 2022-06-30 US claimed
WO-2022134489-A1 FULL CONTINUOUS FLOW SYNTHESIS PROCESS OF FLUORINE-CONTAINING AROMATIC HYDROCARBON COMPOUND 福建中欣氟材高宝科技有限公司 2022-06-30 WO claimed
CN-112608212-B Full continuous flow synthesis process of fluorine-containing aromatic compound 福建中欣氟材高宝科技有限公司 2022-02-08 CN claimed
CN-112608212-A Full continuous flow synthesis process of fluorine-containing aromatic compound 福建高宝矿业有限公司 2021-04-06 CN claimed
CN-107469638-B Sulfonated polyamide composite reverse osmosis membrane for brackish water desalination and preparation method thereof 南京理工大学 2020-01-03 CN claimed
US-9249091-B2 Post-treated sulfurized salt of an alkyl-substituted hydroxyaromatic composition CHEVRON ORONITE COMPANY LLC (US) 2016-02-02 US claimed
US-20130165359-A1 POST-TREATED SULFURIZED SALT OF AN ALKYL-SUBSTITUTED HYDROXYAROMATIC COMPOSITION CHEVRON ORONITE COMPANY LLC (US) 2013-06-27 US claimed
US-7056986-B2 ethylene monomer can be a vinyl ketone, ether, ester, halide, nitrile, aromatic, or an allyl ether; acrylic monomer can be a mono- or diacid or monoester of a diacid; a monoamine, a guanidine compound, and an aromatic diamine; improved vulcanizability, balance between processability and compression set DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2006-06-06 US claimed
US-4094990-A CERTAIN PHYTOFUNGICIDAL N-FURANYL CARBONYL AND TETRAHYDROFURANYL CARBONYL, N-(SUBSTITUTED)PHENYL ALANINES CIBA-GEIGY CORPORATION (US) 1978-06-13 US claimed
EP-4652291-A1 SCARLESS TEMPLATE-FREE ENZYMATIC SYNTHESIS OF POLYNUCLEOTIDES DNA Script (FR) 2025-11-26 EP disclosed
CN-120192204-A Preparation method of fluoro aromatic hydrocarbon compound 阜新孚隆宝医药科技有限公司 2025-06-24 CN disclosed
CN-119504728-A Imidazole-oxazolyl bidentate ligand, synthesis method thereof, metal catalyst prepared from imidazole-oxazolyl bidentate ligand and application of metal catalyst 中国石油化工股份有限公司 2025-02-25 CN disclosed
CN-119462753-A Imidazole-phosphine bidentate ligand, synthesis method thereof, metal catalyst prepared from imidazole-phosphine bidentate ligand and application of metal catalyst 中国石油化工股份有限公司 2025-02-18 CN disclosed
US-4233055-A Quaternary ammonioalkanecarboxylic acid anilides as plant growth influencing agents CIBA-GEIGY CORPORATION (US) 1980-11-11 US disclosed
US-4194008-A INSECTICIDE, FUNGICIDE, MITICIDE, PARASITICIDES BAYER AKTIENGESELLSCHAFT (DE) 1980-03-18 US disclosed
US-4141718-A ANTIGROWTH AGENTS FOR PLANTS CIBA-GEIGY CORPORATION (US) 1979-02-27 US disclosed
US-4094990-A CERTAIN PHYTOFUNGICIDAL N-FURANYL CARBONYL AND TETRAHYDROFURANYL CARBONYL, N-(SUBSTITUTED)PHENYL ALANINES CIBA-GEIGY CORPORATION (US) 1978-06-13 US disclosed
US-4076836-A MICROBIOCIDES CIBA-GEIGY CORPORATION (US) 1978-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130165359-A1 POST-TREATED SULFURIZED SALT OF AN ALKYL-SUBSTITUTED HYDROXYAROMATIC COMPOSITION TST, PAH, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 ALDH1A1 814/4885TSHR 4066/4885CYP3A4 2118/4885
US-20220204427-A1 FULL CONTINUOUS FLOW SYNTHESIS PROCESS OF FLUORINE-CONTAINING AROMATIC HYDROCARBON COMPOUNDS AHR, FGFR2, FGFR1 ALDH1A1 1785/4885TSHR 517/4885CYP3A4 866/4885
US-12071388-B2 Full continuous flow synthesis process of fluorine-containing aromatic hydrocarbon compounds AHR, FGFR2, FGFR1 ALDH1A1 1785/4885TSHR 517/4885CYP3A4 866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.