⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2695677 | 0.74 | — | — | |
| SCHEMBL28635797 | 0.74 | LMNA (0.36) | — | |
| SCHEMBL28870195 | 0.72 | — | — | |
| SCHEMBL14201653 | 0.70 | — | — | |
| SCHEMBL1269510 | 0.70 | — | — | |
| SCHEMBL14797831 | 0.69 | KDM4E (0.36) | — | |
| SCHEMBL2986166 | 0.69 | KDM4E (0.41) | — | |
| SCHEMBL45067 | 0.69 | — | — | |
| SCHEMBL3873381 | 0.67 | TSHR (0.34) | — | |
| SCHEMBL2689936 | 0.67 | TSHR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114797506-B | Preparation method and application of ionized polyimide gas separation membrane | 中国科学院过程工程研究所 | 2023-08-01 | — | — | CN | claimed |
| CN-114797506-A | Preparation method and application of ionized polyimide gas separation membrane | 中国科学院过程工程研究所 | 2022-07-29 | — | — | CN | claimed |
| CN-116387239-A | Method of depositing gap-filling fluid and related systems and devices | ASM IP私人控股有限公司 | 2023-07-04 | — | — | CN | disclosed |
| EP-2013179-A1 | ARYLOXYETHYLAMINE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR | Abbott GmbH & Co. KG (DE) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007118859-A1 | ARYLOXYETHYLAMINE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR | ABBOTT GMBH & CO. KG (DE) | 2007-10-25 | — | — | WO | disclosed |
| EP-1812389-A1 | AZABICYCLOHEPTYL COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR | Abbott GmbH & Co. KG (DE) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006040176-A1 | AZABICYCLOHEPTYL COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR | ABBOTT GMBH & CO. KG (DE) | 2006-04-20 | — | — | WO | disclosed |
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |