N-Formylmethionyl-Leucylphenylalanine

N-Formylmethionyl-Leucylphenylalanine

SCHEMBL39528

CSCCC(NC=O)C(=O)NC(CC(C)C)C(=O)NC(Cc1ccccc1)C(=O)O

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FPR1 P21462 4/20 0.61
FPR2 P25090 4/20 0.61
LTA4H P09960 1/20 0.53
MME P08473 2/20 0.52
MMP2 P08253 1/20 0.50
MMP7 P09237 1/20 0.50
MMP9 P14780 1/20 0.50
MMP12 P39900 1/20 0.50
MMP13 P45452 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Formylmethionyl-Leucylphenylalanine SCHEMBL4592799 1.00 FPR1 (0.61) FPR1FPR2LTA4HMMEMMP2
N-Formylmethionyl-Leucylphenylalanine SCHEMBL17202476 1.00 FPR1 (0.61) FPR1FPR2LTA4HMMEMMP2
N-Formylmethionyl-Leucylphenylalanine SCHEMBL4969844 1.00 FPR1 (0.61) FPR1FPR2LTA4HMMEMMP2
N-Formylmethionyl-Leucylphenylalanine SCHEMBL9903983 1.00 FPR1 (0.61) FPR1FPR2LTA4HMMEMMP2
N-Formylmethionyl-Leucylphenylalanine SCHEMBL7127847 1.00 FPR1 (0.61) FPR1FPR2LTA4HMMEMMP2
N-Formylmethionyl-Leucylphenylalanine SCHEMBL39529 1.00 FPR1 (0.61) FPR1FPR2LTA4HMMEMMP2
SCHEMBL27066372 0.99 FPR1 (0.60) FPR1FPR2LTA4HMMEMMP2
SCHEMBL2413701 0.99 FPR1 (0.60) FPR1FPR2LTA4HMMEMMP2
SCHEMBL27066369 0.94 FPR1 (0.56) FPR1FPR2
SCHEMBL27066397 0.94 FPR1 (0.56) FPR1FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2360 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12492367-B2 Sensor chip capable of culturing cells and of analyzing cell-derived substance, and cell activity quantitative analysis method using the same AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2025-12-09 US claimed
US-20250243445-A1 BIOSENSING CHIP TO ANALYZE CELL-DERIVED MATERIALS DURING CELL CULTURE, AND METHOD FOR QUANTITATIVE ANALYSIS OF CELL ACTIVITY USING THE SAME AJOU UNIVERSITY INDUSTRY-ACDEMIC COOPERATION FOUNDATION (KR) 2025-07-31 US claimed
US-12274704-B2 9,11-secosteroids and the use of 9,11-secosteroids in preparing pharmaceutical compositions for inhibiting inflammation CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) 2025-04-15 US claimed
CN-111330023-B Magnetic nano composite material and preparation method and application thereof 中国科学院宁波材料技术与工程研究所慈溪生物医学工程研究所 2023-01-31 CN claimed
US-11519923-B2 Analyte detection system and method SIEMENS HEALTHINEERS NEDERLAND B.V. (NL) 2022-12-06 US claimed
CN-109416357-B Devices, systems, and methods for detecting an analyte in a bodily fluid sample comprising a plurality of cells 西门子医疗系统荷兰有限公司 2022-07-15 CN claimed
CN-109328302-B Analyte detection systems and methods 西门子医疗系统荷兰有限公司 2022-06-07 CN claimed
EP-3497445-B1 METHODS FOR MICROPATTERNING AND MICROPATTERNED DEVICES IST AUSTRIA INSTITUTE OF SCIENCE AND TECH AUSTRIA (AT) 2022-02-16 EP claimed
US-11125744-B2 Device, system and method for detecting an analyte in a body fluid sample containing a plurality of cells SIEMENS HEALTHINEERS NEDERLAND B.V. (NL) 2021-09-21 US claimed
EP-3826659-A1 USE OF IMMUNOMODULATORS TO CONTROL INFECTION AND STIMULATE HEALING IN NORMAL AND DIABETIC WOUNDS Rush University Medical Center (US) 2021-06-02 EP claimed
US-20030113872-A1 Vasopermeability-enhancing conjugates EPSTEIN ALAN L (US) 2003-06-19 US claimed
US-6524823-B2 Vasopermeability-enhancing conjugates THE UNIVERSITY OF SOUTHERN CALIFORNIA 2003-02-25 US claimed
WO-2002066510-A2 REGAKINE-1 K.U. LEUVEN RESEARCH AND DEVELOPMENT (BE) 2002-08-29 WO claimed
US-6416965-B2 COMBINING COMPOUND WITH PHOSPHOLIPASE D(PLD), TREATING MIXTURE WITH PHOSPHATIDYLCHOLINE SO THAT CLEAVAGE REACTION BETWEEN PHOSPHATIDYLCHOLINE AND PLD CAN OCCUR, RESULTING IN GENERATION OF PHOSPHATIDIC ACID AND CHOLINE, EVALUATING AMOUNT OF CHOLINE BRIGHAM AND WOMEN'S HOSPITAL 2002-07-09 US claimed
US-20020068328-A1 Vasopermeability-enhancing conjugates UNIVERSITY OF SOUTHERN CALIFORNIA, THE 2002-06-06 US claimed
EP-1066834-A2 Pharmaceutical compositions comprising a phagocyte-modulating agent Stief, Thomas, Dr. (DE) 2001-01-10 EP claimed
US-6017537-A IMMUNOLOGICAL ADJUVANTS COMPRISED OF THE N-FORMYL METHIONYL PEPTIDE FMLP USED AS AN ADJUVANT TO PROVIDE FOR AN IMMUNE RESPONSE TO SUBOPTIMAL DOSES OF RECOMBINANT ANTIGENS CONNAUGHT LABORATORIES, INC. (US) 2000-01-25 US claimed
US-6007817-A Vasopermeability enhancing immunoconjugates UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1999-12-28 US claimed
US-5750354-A Lipoxin transport system and uses therefor BRIGHAM AND WOMEN'S HOSPITAL (US) 1998-05-12 US claimed
EP-0438497-B1 VASOPERMEABILITY-ENHANCING CONJUGATES UNIV SOUTHERN CALIFORNIA (US) 1996-03-13 EP claimed