N-Formylmethionyl-Leucylphenylalanine

N-Formylmethionyl-Leucylphenylalanine

SCHEMBL4969844

CSCC[C@H](NC=O)C(=O)NC(CC(C)C)C(=O)NC(Cc1ccccc1)C(=O)O

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FPR1 P21462 4/20 0.61
FPR2 P25090 4/20 0.61
LTA4H P09960 1/20 0.53
MME P08473 2/20 0.52
MMP2 P08253 1/20 0.50
MMP7 P09237 1/20 0.50
MMP9 P14780 1/20 0.50
MMP12 P39900 1/20 0.50
MMP13 P45452 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Formylmethionyl-Leucylphenylalanine SCHEMBL4592799 1.00 FPR1 (0.61) FPR1FPR2LTA4HMMEMMP2
N-Formylmethionyl-Leucylphenylalanine SCHEMBL17202476 1.00 FPR1 (0.61) FPR1FPR2LTA4HMMEMMP2
N-Formylmethionyl-Leucylphenylalanine SCHEMBL39528 1.00 FPR1 (0.61) FPR1FPR2LTA4HMMEMMP2
N-Formylmethionyl-Leucylphenylalanine SCHEMBL9903983 1.00 FPR1 (0.61) FPR1FPR2LTA4HMMEMMP2
N-Formylmethionyl-Leucylphenylalanine SCHEMBL7127847 1.00 FPR1 (0.61) FPR1FPR2LTA4HMMEMMP2
N-Formylmethionyl-Leucylphenylalanine SCHEMBL39529 1.00 FPR1 (0.61) FPR1FPR2LTA4HMMEMMP2
SCHEMBL27066372 0.99 FPR1 (0.60) FPR1FPR2LTA4HMMEMMP2
SCHEMBL2413701 0.99 FPR1 (0.60) FPR1FPR2LTA4HMMEMMP2
SCHEMBL27066369 0.94 FPR1 (0.56) FPR1FPR2
SCHEMBL27066397 0.94 FPR1 (0.56) FPR1FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117919294-A Chrysanthemum extract and application thereof in preparing pharmaceutical composition for inhibiting inflammatory reaction and promoting wound healing 明基材料股份有限公司 2024-04-26 CN disclosed
EP-1162990-B1 TREATMENT WITH SMALL PEPTIDES TO EFFECT ANTIFIBROTIC ACTIVITY MOWYCAL LENDING LLC (US) 2008-11-05 EP disclosed