Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3951701 | 0.91 | HIF1A (0.38) | ALDH1A1KDM4EKMT2AMEN1CYP3A4 | |
| SCHEMBL3950976 | 0.86 | ALDH1A1 (0.46) | ALDH1A1KDM4EKMT2AMEN1CYP3A4 | |
| SCHEMBL3949908 | 0.83 | PIM1 (0.36) | ALDH1A1KDM4EKMT2AMEN1CYP3A4 | |
| Glutaral SCHEMBL3265736 | 0.80 | HIF1A (0.46) | ALDH1A1KDM4EKMT2AHIF1A | |
| SCHEMBL3952508 | 0.80 | PAOX (0.47) | ALDH1A1KMT2AMEN1SIGMAR1HIF1A | |
| SCHEMBL7289625 | 0.80 | TSHR (0.56) | ALDH1A1HTR1ADRD2HTR2ADRD3 | |
| Glutaral SCHEMBL23648822 | 0.80 | ALDH1A1 (0.35) | ALDH1A1KDM4EKMT2AMEN1CYP3A4 | |
| SCHEMBL984275 | 0.79 | HRH3 (0.46) | KCNH2HRH3HIF1APAOX | |
| SCHEMBL986238 | 0.79 | HRH3 (0.46) | KCNH2HRH3HIF1APAOX | |
| SCHEMBL678406 | 0.79 | HRH3 (0.52) | ALDH1A1HRH3HIF1ASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251191-A1 | ONE-COMPONENT DELIVERY SYSTEM FOR NUCLEIC ACIDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2022-12-01 | — | — | WO | disclosed |
| WO-2017046036-A1 | COMPOUNDS FOR THE MODULATION OF RIP2 KINASE ACTIVITY | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-03-23 | — | — | WO | disclosed |
| WO-2009024825-A1 | 2-PYRAZINYLBENZIMIDAZOLE DERIVATIVES AS RECEPTOR TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2009-02-26 | — | — | WO | disclosed |