Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLQ | O75417 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287362 | 0.85 | PPARG (0.48) | PPARGPPARAALDH1A1HPGDCTBP2 | |
| SCHEMBL4964530 | 0.80 | CYP1A2 (0.50) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL4964528 | 0.80 | CYP1A2 (0.50) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL27305323 | 0.80 | PPARG (0.44) | PPARGPPARAALDH1A1HPGDCTBP2 | |
| SCHEMBL679865 | 0.76 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1POLQHTT | |
| SCHEMBL4564576 | 0.76 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1POLQHTT | |
| SCHEMBL27820012 | 0.76 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1POLQHTT | |
| SCHEMBL430659 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL430660 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL7437418 | 0.76 | KMT2A (0.58) | PPARGPPARAALDH1A1HPGDCTBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021354-A2 | N-TERMINALLY MODIFIED GLP-1 RECEPTOR MODULATORS | Brystol-Myers Squibb Company (US) | 2009-02-11 | — | — | EP | disclosed |
| WO-2007140284-A2 | N-TERMINALLY MODIFIED GLP-1 RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-12-06 | — | — | WO | disclosed |