SCHEMBL287362

SCHEMBL287362

Cc1ccccc1CC(C(=O)O)N(C)C

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.48
PPARA Q07869 1/20 0.48
ALDH1A1 P00352 3/20 0.42
HPGD P15428 1/20 0.42
CTBP2 P56545 1/20 0.42
MAPT P10636 1/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
HTT P42858 1/20 0.40
GAA P10253 1/20 0.40
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6671785 0.87 ESR1 (0.40) PPARGPPARAALDH1A1MAPTKMT2A
SCHEMBL14947768 0.86 PPARG (0.41) PPARGPPARAALDH1A1HPGDCTBP2
SCHEMBL3955417 0.85 PPARG (0.45) PPARGPPARAALDH1A1HPGDCTBP2
SCHEMBL27305323 0.84 PPARG (0.44) PPARGPPARAALDH1A1HPGDCTBP2
SCHEMBL15772413 0.83 KMT2A (0.42) PPARGALDH1A1HPGDMAPTKMT2A
SCHEMBL27556049 0.81 ALDH1A1 (0.49) PPARGPPARAALDH1A1MAPTKMT2A
SCHEMBL3955410 0.80 KMT2A (0.65) PPARGPPARAALDH1A1MAPTKMT2A
SCHEMBL7437418 0.80 KMT2A (0.58) PPARGPPARAALDH1A1HPGDCTBP2
SCHEMBL7435174 0.79 MMP13 (0.44) PPARGPPARAALDH1A1HPGDCTBP2
SCHEMBL7406460 0.79 PPARG (0.43) PPARGPPARAALDH1A1HPGDCTBP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022075354-A1 A METHOD FOR OBTAINING AN INDEX FOR THE DIAGNOSIS OF ALZHEIMER'S DISEASE (AD) OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) 2022-04-14 WO claimed
US-20260137717-A1 TREATMENT FOR GINGIVITIS THE UNIVERSITY OF MELBOURNE (AU) 2026-05-21 US disclosed
US-20260115109-A1 STABILIZED STANNOUS COMPOSITIONS THE UNIVERSITY OF MELBOURNE (AU) 2026-04-30 US disclosed
US-12569417-B2 Compositions and methods for promoting mineralization THE UNIVERSITY OF MELBOURNE (AU) 2026-03-10 US disclosed
US-12551417-B2 Stabilized stannous compositions THE UNIVERSITY OF MELBOURNE (AU) 2026-02-17 US disclosed
US-12303548-B2 Complexes for treating sensitivity THE UNIVERSITY OF MELBOURNE (AU) 2025-05-20 US disclosed
US-20250152666-A1 COMPLEXES FOR TREATING SENSITIVITY THE UNIVERSITY OF MELBOURNE (AU) 2025-05-15 US disclosed
WO-2025097213-A1 COMPOSITIONS AND METHODS FOR TREATING HALITOSIS THE UNIVERSITY OF MELBOURNE (AU) 2025-05-15 WO disclosed
US-20250152482-A1 STABILIZED STANNOUS COMPOSITIONS THE UNIVERSITY OF MELBOURNE (AU) 2025-05-15 US disclosed
US-12239723-B2 Stabilized stannous compositions THE UNIVERSITY OF MELBOURNE (AU) 2025-03-04 US disclosed
WO-2001045746-A2 METHODS AND COMPOSITIONS FOR PROLONGING ELIMINATION HALF-TIMES OF BIOACTIVE COMPOUNDS GENENTECH, INC. (US) 2001-06-28 WO disclosed
EP-1105475-A1 TISSUE FACTOR PROTEIN VARIANTS WITH INCREASED AFFINITY FOR COAGULATION FACTOR FVII/FVIIA Genentech, Inc. (US) 2001-06-13 EP disclosed
WO-2001010892-A2 PEPTIDE ANTAGONISTS OF FACTOR VIIA GENENTECH, INC. (US) 2001-02-15 WO disclosed
WO-2001001749-A2 FVIIa ANTAGONISTS GENENTECH, INC. (US) 2001-01-11 WO disclosed
WO-2000078801-A2 INSULIN-LIKE GROWTH FACTOR AGONIST MOLECULES GENENTECH, INC. (US) 2000-12-28 WO disclosed
WO-2000068363-A2 ELASTASE VARIANTS AND SUBSTRATES GENENTECH, INC. (US) 2000-11-16 WO disclosed
US-6028055-A USE IN TREATMENT OR PROPHYLAXIS OF VARIOUS PATHOLOGICAL CONDITIONS ASSOCIATED WITH WATER OR ELECTROLYTE IMBALANCE GENETECH, INC. (US) 2000-02-22 US disclosed
WO-2000004148-A1 TISSUE FACTOR PROTEIN VARIANTS WITH INCREASED AFFINITY FOR COAGULATION FACTOR FVII/FVIIA GENENTECH, INC. (US) 2000-01-27 WO disclosed
EP-0939770-A1 RECEPTOR SPECIFIC BRAIN NATRIURETIC PEPTIDE (BNP) Genentech, Inc. (US) 1999-09-08 EP disclosed
WO-1998017690-A1 RECEPTOR SPECIFIC BRAIN NATRIURETIC PEPTIDE (BNP) GENENTECH, INC. (US) 1998-04-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137717-A1 TREATMENT FOR GINGIVITIS ACP3, FIBP, FGF23 PPARG 508/4885PPARA 1520/4885ALDH1A1 4794/4885
US-20260115109-A1 STABILIZED STANNOUS COMPOSITIONS CHERP, FIBP, ACP3 PPARG 2518/4885PPARA 2950/4885ALDH1A1 4733/4885
US-12551417-B2 Stabilized stannous compositions CHERP, CA3, CA2 PPARG 2686/4885PPARA 3006/4885ALDH1A1 4715/4885
US-12569417-B2 Compositions and methods for promoting mineralization CA3, FIBP, ACP3 PPARG 1463/4885PPARA 2816/4885ALDH1A1 3475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.