SCHEMBL39557

SCHEMBL39557

COc1ccc2nccc(C(=O)O)c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 1.00
KDM4E B2RXH2 4/20 0.76
MAPK1 P28482 1/20 0.65
NPSR1 Q6W5P4 1/20 0.65
ALDH1A1 P00352 1/20 0.64
POLB P06746 1/20 0.64
HPGD P15428 1/20 0.64
HSD17B10 Q99714 1/20 0.64
CYP1A2 P05177 1/20 0.59
KDM4C Q9H3R0 5/20 0.56
MTNR1A P48039 3/20 0.53
MTNR1B P49286 3/20 0.53
KDM5A P29375 3/20 0.53
KDM5B Q9UGL1 2/20 0.53
SLC22A12 Q96S37 1/20 0.53
PLA2G2A P14555 2/20 0.50
DDR2 Q16832 1/20 0.50
HTR1A P08908 1/20 0.50
ADRA1D P25100 1/20 0.50
ADRA1A P35348 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30120700 1.00 LMNA (1.00) LMNAKDM4EMAPK1NPSR1ALDH1A1
Hydrochloric Acid SCHEMBL9081231 0.98 LMNA (0.97) LMNAKDM4EMAPK1NPSR1ALDH1A1
SCHEMBL29048387 0.98 LMNA (0.97) LMNAKDM4EMAPK1NPSR1ALDH1A1
Hydrochloric Acid SCHEMBL28580096 0.98 LMNA (0.97) LMNAKDM4EMAPK1NPSR1ALDH1A1
SCHEMBL4353000 0.98 LMNA (0.97) LMNAKDM4EMAPK1NPSR1ALDH1A1
SCHEMBL3074710 0.98 LMNA (0.97) LMNAKDM4EMAPK1NPSR1ALDH1A1
Ammonia Solution, Strong SCHEMBL1760797 0.98 LMNA (0.97) LMNAKDM4EMAPK1NPSR1ALDH1A1
SCHEMBL3076842 0.98 LMNA (0.97) LMNAKDM4EMAPK1NPSR1ALDH1A1
SCHEMBL3079277 0.98 LMNA (0.97) LMNAKDM4EMAPK1NPSR1ALDH1A1
SCHEMBL3079376 0.98 LMNA (0.97) LMNAKDM4EMAPK1NPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 16934 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121674302-B Lactobacillus plantarum, zhong Huang ferment, preparation method and application thereof in improving bone health Hunan Nutrition Tree Biotechnology Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122071541-A Carboxylated nitrile rubber or carboxylated hydrogenated nitrile rubber and preparation method thereof 中石油(上海)新材料研究院有限公司 2026-05-22 CN claimed
CN-122070479-A Ultrasonic indicating device and method for monitoring ultrasonic treatment JP实验室股份有限公司 2026-05-19 CN claimed
US-12630520-B2 Left-handed bicyclic morpholine and salt thereof, preparation method therefor, pharmaceutical composition, and use INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2026-05-19 US claimed
US-20260130395-A1 Water Dispersible Botanical Compositions AQUILA BLACK LTD (AU) 2026-05-14 US claimed
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
CN-119685827-B Environment-friendly composite corrosion and scale inhibitor and preparation method and application thereof 中国石油化工股份有限公司 2026-05-12 CN claimed
US-12622889-B2 S-β-hydroxybutyrate esters for improving metabolic function AXCESS GLOBAL SCIENCES, LLC (US) 2026-05-12 US claimed
CN-122017247-A Plasma metabolism marker for distinguishing benign thyroid diseases from early thyroid cancers and application of plasma metabolism marker 哈尔滨脉图精准技术有限公司 2026-05-12 CN claimed
CN-122005700-A Traditional Chinese medicine composition for treating skin inflammation and preparation method and application thereof 马文平 2026-05-12 CN claimed
EP-0132877-A2 Ultrafast roasted coffee THE PROCTER & GAMBLE COMPANY (US) 1985-02-13 EP claimed
US-4426448-A PREPARARATION OF CAFFEIC ACID KIKKOMAN CORPORATION (JP) 1984-01-17 US claimed
US-4370416-A CULTIVATION OF ASPERGILLUS OR BOTRYTIS KIKKOMAN CORPORATION (JP) 1983-01-25 US claimed
US-4367224-A ANTIINFLAMMATORY AGENTS, SKIN DISORDERS SCOTT EUGENE J VAN 1983-01-04 US claimed
US-4363815-A Alpha hydroxyacids, alpha ketoacids and their use in treating skin conditions YU RUEY J 1982-12-14 US claimed
US-4353912-A NEUROLEPTIC AGENTS NORTHEASTERN UNIVERSITY (US) 1982-10-12 US claimed
US-4145255-A ENZYMATIC OXIDATION THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1979-03-20 US claimed
US-4123400-A B-DIKETONES, A POLYOL, ORGANO-METALLIC SALTS RHONE-POULENC INDUSTRIES (FR) 1978-10-31 US claimed
US-3974197-A HYDROXY CARBOXYLIC ACIDS, FERRIC IONS, YELLOW, FOOD GENERAL FOODS CORPORATION (US) 1976-08-10 US claimed
US-3958982-A WITH A REAGENT OF FRUIT JUICES OR ORGANIC COMPLEXING AGENT HUANG WEN H 1976-05-25 US claimed